Biological Indicator Reader GUI for Accurate Fluorescence Validation

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Solution Overview

Problem

Current biological indicator readers provide inaccurate results on whether the proper conditions were met to kill a specified number of microorganisms during sterilization processes, leading to potential contamination risks.

Innovation Solution

A biological indicator reader system that includes a housing with multiple holders, a heater to incubate indicators, a UV light emitter, and an optical detector to detect fluorescence intensity, providing accurate results on sterilization process effectiveness through a graphical user interface.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional biological indicator readers are used to detect sterilization effectiveness, then the sterilization process can be monitored, but the results are inaccurate and cannot provide confidence in the sterilization process

Engineering Contradiction:
Improvesterilization effectiveness detection accuracyVSAvoidconfidence in sterilization process
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The system incorporates a graphical user interface that provides real-time feedback on sterilization process parameters including temperature, humidity, and fluorescence intensity. The controller continuously monitors these parameters and provides visual feedback through the GUI to indicate whether sterilization conditions are being met, allowing operators to adjust parameters to achieve accurate and reliable results

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system enables dynamic adjustment of sterilization parameters including temperature, humidity, and UV light intensity through the graphical user interface. By allowing real-time parameter changes and optimization, the system can adapt to different biological indicator types and sterilization conditions to achieve accurate fluorescence detection and reliable sterilization validation

Inventive Principle:
Principle #35Parameter changes

2Device complexity

If a simple biological indicator reader is used, then the device complexity is reduced, but the ability to accurately detect fluorescence and provide reliable sterilization validation is compromised

Engineering Contradiction:
Improvereader system structureVSAvoidfluorescence detection accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The biological indicator reader is designed as a multi-functional system that combines incubation, fluorescence detection, parameter monitoring, and graphical user interface capabilities in a single device. This universal design allows the system to perform multiple functions without requiring separate complex devices, achieving accurate fluorescence detection while maintaining reasonable system integration

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The graphical user interface acts as an intermediary between the complex internal systems (heater, UV emitter, optical detector, controller) and the user. It simplifies the interaction by presenting processed information in an understandable format and allowing users to control parameters without needing to understand the underlying complex mechanisms, thus reducing perceived device complexity while maintaining measurement precision

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system ensures reliable detection of sterilization failures by accurately measuring fluorescence intensity, reducing inaccurate results and enhancing user confidence in sterilization processes.

Implementation Method 1

a heater coupled to the housing and configured to heat the plurality of biological indicator holders to a preselected temperature to incubate the biological indicators

Methodology Applied
Scientific EffectHeating: Heating

Implementation Method 2

a UV light emitter configured to emit UV light through the first aperture of each holder

Methodology Applied
Scientific EffectUV light emission: Light Emitting Diode

Implementation Method 3

an optical detector positioned adjacent to the second aperture of the biological indicator holder, the optical detector configured to detect fluorescence intensity indicating the effectiveness of the sterilization process

Methodology Applied
Scientific EffectFluorescence detection: Fluorescence

Data Source

PatentUS12616769B2Biological indicator reader with graphical user interface and methods of use
Publication Date: 2026.05.05 CROSSTEX INTERNATIONAL INC
  • US12616769B2 patent drawing
  • US12616769B2 patent drawing
  • US12616769B2 patent drawing

AI summary

A biological indicator reader is provided for reading a plurality of biological indicators to determine the effectiveness of at least a sterilization process. Each biological indicator is configured to exhibit fluorescence when the sterilization process has failed. Each reader comprises a housing having a plurality of biological indicator holders, a heater coupled to the housing and configured to heat the plurality of biological indicator holders to a preselected temperature to incubate the biological indicators, a UV light emitter configured to emit UV light through a first aperture on the side of each holder and an optical detector positioned under a second aperture on the bottom of the biological indicator holder, the optical detector configured to detect fluorescence intensity indicating the effectiveness of the sterilization process. A method of using the biological indicator reader is provided. A biological indicator system and display are also provided.