Biological Information Measurement System Using Phase-Specific Signal Processing

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Solution Overview

Problem

Current biological information measurement systems using pulse photometers are inefficient in quickly and accurately measuring various types of biological information, particularly in distinguishing the effects of arterial and venous blood flow, which limits their ability to calculate concentrations of light-absorbing substances and transit times in blood.

Innovation Solution

A biological information measurement system that emits light at multiple wavelengths, differentiates signals to identify dominant phases of arterial and venous blood flow, and sets processing periods accordingly to calculate concentrations and transit times with reduced calculation loads, allowing for high-speed measurement without the need for invasive indicators.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the conventional pulse photometer method is used to measure biological information, then the measurement can be performed non-invasively, but the measurement speed is slow and the calculation load is high

Engineering Contradiction:
Improvemeasurement speedVSAvoidcalculation load
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent segments the cardiac cycle into distinct phases (systole and diastole) and processes optical signals separately for each phase. By dividing the continuous signal processing into discrete temporal segments corresponding to arterial inflow and venous outflow phases, the system achieves faster measurement while reducing computational complexity through phase-specific analysis.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent performs preliminary identification of systolic and diastolic phases before conducting detailed concentration calculations. By pre-segmenting the cardiac cycle and identifying dominant blood flow phases in advance, the system prepares data structures and processing parameters that enable rapid subsequent calculation of light-absorbing substance concentrations without requiring complex real-time analysis.

Inventive Principle:
Principle #10Preliminary action

2Productivity

If the conventional method processes the entire cardiac cycle, then comprehensive blood flow information is obtained, but the processing time increases and measurement efficiency decreases

Engineering Contradiction:
Improvemeasurement efficiencyVSAvoidprocessing time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent extracts and processes only the essential systolic and diastolic phases from the complete cardiac cycle, discarding redundant information. By taking out the critical phases where arterial and venous blood flow effects are dominant, the system achieves efficient measurement of light-absorbing substance concentrations without the need to process the entire cardiac cycle, thereby reducing processing time while maintaining measurement accuracy.

Inventive Principle:
Principle #2Taking out (Extraction)

3Adaptability or versatility

If multiple wavelengths are used to measure different light-absorbing substances, then measurement versatility improves, but signal differentiation and processing complexity increases

Engineering Contradiction:
Improvemeasurement versatilityVSAvoidsignal processing complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent applies local quality by assigning different wavelength combinations to different cardiac phases and measurement targets. Specific wavelengths are optimized for detecting oxyhemoglobin during systole, while other wavelengths are used for deoxyhemoglobin detection during diastole. This localized wavelength assignment reduces signal processing complexity by matching measurement parameters to specific physiological phases and targets.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent dynamically changes processing parameters including wavelength selection, gain settings, and analysis algorithms based on the identified cardiac phase and target analyte. By adjusting parameters according to the specific measurement context (systole vs. diastole, oxyhemoglobin vs. deoxyhemoglobin), the system achieves versatile multi-substance measurement while keeping processing complexity manageable through context-adaptive parameter selection.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables rapid and accurate measurement of biological information, including light-absorbing substance concentrations and transit times, by distinguishing between arterial and venous blood flow phases, thereby improving the efficiency of pulse photometer-based measurements.

Implementation Method 1

a photoreception unit outputting a first signal and a second signal depending on photoreception intensity of the first light and photoreception intensity of the second light transmitted through or reflected by biological tissue of a subject

Methodology Applied
Scientific EffectPhotoreception: Photoelectric Effect

Data Source

PatentUS10548493B2Biological information measurement system
Publication Date: 2020.02.04 NIHON KOHDEN CORP
  • US10548493B2 patent drawing
  • US10548493B2 patent drawing
  • US10548493B2 patent drawing

AI summary

A light emitting unit emits first light and second light having different wavelengths. A photoreception unit outputs first and second signals depending on photoreception intensities of the first and second light transmitted through or reflected by biological tissue. A processing period setting unit extracts a signal cycle corresponding to the cardiac cycle for the first or second signal and sets a processing period in a first part dominantly affected by arterial blood flowing to the tissue or a second part dominantly affected by venous blood flowing from the tissue in the signal cycle. First and second change amount acquisition units obtain first and second change amounts corresponding to the attenuation change amounts of the first and second light from the first and second signals in the processing period. A concentration calculation unit calculates the concentration of light absorbing substance in blood from the first and second change amounts.