Biological Sample Analysis System with Temporal Data Visualization
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Conventional analyzing systems require cumbersome tasks to evaluate temporal changes in compound concentrations in culture supernatants, making it difficult to compare results from samples derived from the same or different cell types cultured under varying conditions, and lack detailed checking of individual quantitative values.
Innovation Solution
A biological sample analyzing system that includes an analyzing device for signal-intensity-value data acquisition, a quantitative analyzer for calculating compound concentrations, an analysis result storage section, a table creator for organizing data, a graph creator for visualizing temporal changes, and a display processor to show tables and graphs on the same screen, allowing for easy comparison and detailed inspection of quantitative values.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional analyzing systems are used to evaluate temporal changes in compound concentrations, then analysis can be performed, but operators must perform cumbersome tasks including manually searching for analysis results and creating graphs, which increases time and labor requirements
Solution Approach 1:
The system automatically retrieves analysis results from the storage section, organizes them by sampling time, and generates graphs without operator intervention. The automatic graph creator function enables the system to serve itself by performing tasks that would otherwise require manual operator effort, thus reducing time and labor while maintaining evaluation accuracy
Solution Approach 2:
The patent introduces an automatic graph creator and result retrieval function as an intermediary between the analysis result storage section and the display section. This intermediary automatically processes raw analysis data, organizes it temporally, and presents it in graphical form, eliminating the need for operators to manually search and create graphs
2Adaptability or versatility
If conventional analyzing systems are used, then analysis results can be obtained, but it is difficult to compare results from samples derived from the same or different cell types cultured under varying conditions
Solution Approach 1:
The system provides a universal comparison framework that can handle samples from the same cell type under different conditions, different cell types under the same conditions, and different cell types under different conditions. The automatic graph creator and table organizer present data in a standardized format that facilitates versatile comparison across all sample types without requiring separate analysis procedures
Solution Approach 2:
The patent adds the time dimension by automatically organizing and displaying analysis results in temporal sequence through graphs and tables. This temporal dimension enables operators to easily track changes in compound concentrations over time and compare trends across different samples, transforming static data into dynamic visual comparisons
3Measurement precision
If conventional analyzing systems are used, then quantitative analysis can be performed, but detailed checking of individual quantitative values is lacking
Solution Approach 1:
The system segments the presentation of quantitative data by organizing it in both tabular format (showing individual values) and graphical format (showing trends). This segmentation allows operators to view detailed individual quantitative values in tables while simultaneously observing overall trends in graphs, ensuring no information is lost and enabling detailed checking of specific values
Data Source
AI summary
A data storage section stores LC/MS analysis data for a large number of culture-medium samples acquired with an LC-MS. Based on those data, a quantitative analyzer calculates concentration values of a large number of compounds in each sample and stores the result in an analysis result storage section. A result display processor retrieves analysis results with the same culture name and different sampling date from the analysis result storage section, creates a table in which concentration values are arranged for each compound and for each sampling date, as well as a graph showing a temporal change in the concentration value of one compound, and displays the table and graph on the same window on a display unit. An operator using an operation unit selects a compound on the displayed table. The result display processor creates a graph for the selected compound and renews the graph on the display.