Mechanically Actuated Biological Sample Collection Device

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Solution Overview

Problem

Conventional biological sample collection devices are not portable or mechanically actuated, and lack an internally automated collecting and measuring system visible to the user.

Innovation Solution

A sample processing device with a housing that includes a sample chamber, a reagent chamber, and plungers actuated by an external mechanical system to mix and dispense biological samples with reagents, featuring a filter and capillary tube for sample collection and processing, allowing for automated collection, dilution, and measurement.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If conventional devices are used for biological sample collection, then the device structure is simple, but the device is not portable and lacks mechanical actuation capability

Engineering Contradiction:
Improveportability and mechanical actuationVSAvoiddevice structure
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The device employs a nested structure where the plunger assembly is contained within the housing, and the sample collection mechanism is integrated within the plunger system. This nesting approach enables portable, mechanically actuated operation while maintaining compact dimensions suitable for field use.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The device transitions from a static conventional structure to a dynamic mechanically actuated system. The plunger can be manually operated to move between positions, enabling mechanical actuation of the sample collection and processing functions, thereby improving ease of operation in portable settings.

Inventive Principle:
Principle #15Dynamics

2Extent of automation

If conventional collection devices are used, then the device is simple, but there is no internally automated collecting and measuring system visible to the user

Engineering Contradiction:
Improveautomated collecting and measuring systemVSAvoidinternal system structure
Core Design Contradiction:
Extent of automationVSDevice complexity

Solution Approach 1:

The device incorporates an internally automated system where the plunger mechanism automatically performs sample collection, transfer, and measurement functions without requiring external intervention. The system self-regulates the sample processing workflow, providing automation while keeping the internal structure integrated and manageable.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The plunger assembly serves multiple functions: it acts as a mechanical actuator for sample collection, a transfer mechanism for moving samples between chambers, and a measurement indicator system. This multi-functionality enables automated collecting and measuring within a single integrated component structure.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If manual sample collection is used, then the device structure is simple, but the collection efficiency and measurement accuracy are reduced

Engineering Contradiction:
Improvesample collection and processing efficiencyVSAvoidmechanical actuation system
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The device is pre-configured with the plunger in a starting position and the sample chambers prepared before use. The mechanical actuation system is pre-assembled with all necessary components (plunger, seal, filter) in place, enabling immediate efficient operation without requiring complex assembly or setup procedures during actual sample collection.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables portable, mechanically actuated, and user-visible automated collection, dilution, and measurement of biological samples, improving efficiency and usability in sample processing and diagnostics.

Implementation Method 1

a filter positioned within the sample collection area to capture particles

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 2

a capillary tube to draw a biological sample into the collection chamber

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Data Source

PatentUS12019065B2Methods and systems to collect a biological sample
Publication Date: 2024.06.25 NIGHTINGALE HEALTH OYJ
  • US12019065B2 patent drawing
  • US12019065B2 patent drawing
  • US12019065B2 patent drawing

AI summary

Sample processing methods and systems to collect a biological sample. A device may be configured collect a predetermined volume of a sample in sample chamber and seal the chamber upon activation. The device may be further configured to mix the mix the sample with a predetermined volume of a reagent and/or mix the sample and the reagent in a pre-determined ratio.