Biological Sample Collection Device with Automated Mixing

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Solution Overview

Problem

Conventional biological sample collection devices are not portable or mechanically actuated, and lack an internally automated collecting and measuring system visible to the user.

Innovation Solution

A sample processing device with a housing that includes a sample chamber, a reagent chamber, and plungers actuated by an external mechanical system to mix and dispense biological samples with reagents, featuring a filter and capillary tube for sample collection and processing, allowing for automated collection, dilution, and measurement.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Extent of automation

If conventional devices are used for biological sample collection, then the device structure is simple, but the device is not portable and lacks automated collection and measuring systems

Engineering Contradiction:
Improveautomated collection and measuring systemVSAvoiddevice structure
Core Design Contradiction:
Extent of automationVSDevice complexity

Solution Approach 1:

The patent combines multiple functions (sample collection, filtration, capillary tube insertion, and measurement) into a single integrated device. The housing incorporates a sample collection well, filter, capillary tube port, and measurement markings all in one structure, eliminating the need for separate collection devices and reducing overall system complexity despite adding automation capabilities.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The device performs multiple functions simultaneously: it collects biological samples, filters them, provides a port for capillary tube insertion, and includes measurement markings for volume assessment. This multi-functionality reduces the number of separate devices needed while maintaining portability and adding automated capabilities.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Ease of operation

If conventional devices are used for biological sample collection, then the device is easy to manufacture, but it lacks mechanical actuation and portable design

Engineering Contradiction:
Improveportable and mechanically actuatedVSAvoidmanufacturing complexity
Core Design Contradiction:
Ease of operationVSEase of manufacture

Solution Approach 1:

The device is divided into distinct functional segments within a single housing: sample collection well, filter section, capillary tube port, and measurement area. This segmentation allows for modular manufacturing of components while maintaining portability and mechanical actuation capabilities, making the device easier to operate despite increased manufacturing complexity.

Inventive Principle:
Principle #1Segmentation

3Productivity

If automated collection and measuring system is added, then sample processing efficiency is improved, but device complexity increases

Engineering Contradiction:
Improvesample processing efficiencyVSAvoidinternal system complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The device incorporates passive mechanical features that automatically perform functions: the capillary tube is drawn into the well by surface tension and adhesion forces without mechanical actuation, the filter automatically separates sample components, and the measurement markings provide automatic volume indication. This self-service approach improves sample processing efficiency while minimizing the need for complex active mechanical systems.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables portable, mechanically actuated, and user-visible automated collection, dilution, and measurement of biological samples, improving efficiency and usability in sample processing and diagnostics.

Implementation Method 1

a capillary tube to collect a biological sample

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Data Source

PatentUS10180421B2Methods and systems to collect a biological sample
Publication Date: 2019.01.15 NIGHTINGALE HEALTH OYJ
  • US10180421B2 patent drawing
  • US10180421B2 patent drawing
  • US10180421B2 patent drawing

AI summary

Sample processing methods and systems to collect a biological sample. A device may be configured collect a predetermined volume of a sample in sample chamber, and seal the chamber upon activation. The device may be further configured to mix the mix the sample with a predetermined volume of a reagent and/or mix the sample and the reagent in a pre-determined ration.