Biological Sheet Storage with Segmented Carriers and Protective Liquid
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Solution Overview
Problem
Current storage devices are not designed to handle biological sheets effectively, leading to damage during transportation and storage due to lack of suitable carriers and protection mechanisms, which complicates their clinical application.
Innovation Solution
A biological sheet storage device comprising a holding unit with a first carrier, a second carrier, and a fixture that fixes the biological sheet, along with an enclosure that provides all-round protection, using a carrier film with tissue compatibility and a rotating mechanism for easy engagement and disengagement, and a protective liquid like dimethyl sulfoxide for low-temperature storage.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional storage devices are used for biological sheets, then storage is possible, but damage occurs during transportation and storage due to lack of suitable carriers and protection mechanisms
Solution Approach 1:
The storage device is divided into multiple functional components: a first carrier film for holding the biological sheet, a second carrier for supporting the first carrier, and a fixture with pressing plates for fixation. This segmentation allows each component to perform its specific function optimally, preventing damage during storage and transportation
Solution Approach 2:
The enclosure is filled with protective liquid that surrounds the holding unit, providing beforehand cushioning and protection against mechanical shocks and damages during transportation. The pressing plates also apply gentle pressure to secure the biological sheet in position before transportation begins
2Reliability
If a fixture with pressing plates is used to fix the first carrier, then the biological sheet is secured, but the structure becomes more complex
Solution Approach 1:
The fixture is designed as a separate, removable component that can be easily attached and detached from the second carrier. The pressing plates are connected via rotatable connectors, allowing the fixture to be taken out as a modular unit for cleaning, maintenance, or adjustment without disassembling the entire storage device
Solution Approach 2:
The pressing plates are connected to the second carrier through rotatable connectors, enabling the fixture to be rotated into different positions. This dynamic design allows the pressing plates to be adjusted or removed as needed, reducing structural complexity while maintaining reliable fixation when engaged
3Reliability
If an enclosure with protective liquid is used, then protection against damage is improved, but the device complexity increases
Solution Approach 1:
The enclosure is designed as a flexible bag made of heat-conductive material that can be filled with protective liquid. This flexible shell design provides comprehensive protection against shocks and damages while maintaining a relatively simple structure compared to rigid enclosures with complex mechanical protection mechanisms
Solution Approach 2:
The protective liquid acts as an intermediary between the holding unit containing the biological sheet and the external environment. It absorbs shocks and provides thermal protection, reducing the need for complex mechanical protection structures in the enclosure
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device prevents damage to biological sheets during storage and transportation, maintaining their three-dimensional structure and biological activity, enabling long-term storage and transportation without wear, tear, or wrinkling.
Implementation Method 1
the corresponding side edges of the first diaphragm and the second diaphragm are connected through a heat conductive material so that the first diaphragm and the second diaphragm form a bag
Implementation Method 2
a protective liquid like dimethyl sulfoxide for low-temperature storage
Data Source
AI summary
An embodiment of the present disclosure provides a biological sheet storage device, which includes a holding unit including a first carrier, a second carrier and a fixture. The first carrier is configured to carry a biological sheet, the first carrier is positioned on the second carrier, and the fixture is configured to fix the first carrier onto the second carrier. An enclosure configured to enclose the holding unit that is configured to carry the biological sheet.