Biological Sheet Storage with Fixation and Limiting Mechanism
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Solution Overview
Problem
Current storage devices are not designed to handle biological sheets, which are essential in tissue engineering, and existing cell storage devices cannot meet the requirements for storage and transportation of biological sheets like cell sheets, skin samples, or tissue samples, as they lack the necessary protection and compatibility.
Innovation Solution
A biological sheet storage device comprising a fixation arrangement with a first carrier, a second carrier, and a fixing piece, along with a storage box that includes a limiting mechanism, which prevents damage during transportation and provides all-round protection, using materials with tissue compatibility and a rotating mechanism for easy engagement and separation, and heat conductive elements for temperature control.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If existing cell storage devices are used for biological sheets, then storage function is provided, but protection and compatibility requirements cannot be met
Solution Approach 1:
The storage device is segmented into multiple functional components: a first carrier directly contacting the biological sheet, a second carrier providing structural support, and a fixing piece securing the assembly. This segmentation allows each component to be optimized for its specific function, ensuring both protection and compatibility.
Solution Approach 2:
The first carrier acts as an intermediary between the biological sheet and the storage environment. It provides direct contact and protection to the biological sheet while being compatible with tissue, solving the contradiction between protection capability and material compatibility.
2Reliability
If biological sheets are stored without specialized fixation, then storage simplicity is maintained, but damage during transportation occurs
Solution Approach 1:
The fixing piece is designed to be movable rather than fixed, allowing it to adapt to the biological sheet's position and shape. This dynamic fixation mechanism provides reliable securing without requiring complex rigid structures.
Solution Approach 2:
The first carrier is designed as a thin, flexible film that can conform to the biological sheet's surface. This flexible structure provides protection while maintaining simplicity and avoiding complex rigid fixation mechanisms.
3Reliability
If standard storage containers are used, then ease of operation is maintained, but all-round protection cannot be provided
Solution Approach 1:
The rotating mechanism enables dynamic engagement and separation of the fixing piece with the second carrier. This allows easy operation through simple rotation while providing comprehensive protection when engaged.
Solution Approach 2:
The rotating mechanism replaces complex mechanical fastening systems with a simple rotational motion. This substitution maintains ease of operation while achieving reliable engagement for comprehensive protection.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device effectively protects biological sheets from damage, maintains their structure and biological activity during long-term storage and transportation, ensuring they remain unworn, untearred, and unwrinkled, while supporting cryopreservation and long-distance transport.
Implementation Method 1
the cover body comprises at least one heat conductive element which can extend into the box body for conducting heat so as to reduce the temperature in the box body
Data Source
AI summary
A biological sheet storage device includes a fixation arrangement and a storage box. The fixation arrangement includes a first carrier, a second carrier and a fixing piece. The first carrier is configured to carry a biological sheet and positioned on the second carrier. The fixing piece is configured to fix the first carrier on the second carrier. The storage box is configured to encapsulate the fixation arrangement carrying the biological sheet. A limiting mechanism for limiting the fixation arrangement is included in the storage box.