Biomolecule Magnetic Sensor Dimensional Decoupling
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Solution Overview
Problem
Magnetic sensing elements in magnetic sensors are susceptible to interference from external magnetic fields generated by magnetic force generators, which complicates the accurate detection of biomolecules attached to magnetic beads.
Innovation Solution
A biomolecule magnetic sensor configuration that includes an adsorption pad, a magnetic field line generator, and a magnetic sensor, where the magnetic sensor is positioned on second magnetic field lines generated by the magnetic beads, with shifts in both vertical and horizontal directions to minimize interference from the magnetic field line generator, allowing for the detection of magnetic field components in a horizontal direction.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If a magnetic field line generator is used to apply external magnetic field to magnetic beads, then magnetic beads can generate additional magnetic field for detection, but magnetic sensing elements are influenced by the external magnetic field generated by the magnetic field line generator
Solution Approach 1:
The patent applies dimensional separation by configuring the magnetic field line generator to produce magnetic field lines primarily in a first direction (vertical), while the magnetic sensor detects magnetic field components in a second direction (horizontal). This directional decoupling allows the magnetic beads to be effectively actuated by the external magnetic field while the sensor remains relatively immune to direct interference from the generator's primary magnetic field, resolving the contradiction between enabling magnetic field application and avoiding sensor interference
Solution Approach 2:
The patent implements local quality differentiation by creating distinct magnetic field line configurations in different spatial regions. The magnetic field line generator produces concentrated magnetic field lines passing through the magnetic beads in the first direction, while the magnetic sensor is positioned to detect magnetic field components in the second direction where the generator's direct magnetic field influence is minimized. This spatial and directional differentiation allows each component to function optimally without mutual interference
2Volume of moving object
If magnetic sensor is positioned close to adsorption pad for compact design, then device size is reduced, but magnetic sensor is more susceptible to interference from magnetic field line generator
Solution Approach 1:
The patent resolves the proximity issue by transitioning the detection approach to a different dimensional orientation. Instead of positioning the sensor at a greater distance to avoid interference, the sensor is placed close to the adsorption pad but oriented to detect magnetic field components in the horizontal direction, while the magnetic field line generator primarily produces vertical magnetic field lines. This dimensional orthogonality allows compact integration while maintaining interference immunity
Solution Approach 2:
The patent applies local quality by creating directionally selective magnetic field interactions in the compact sensor configuration. The magnetic sensor is positioned close to the adsorption pad but configured to respond primarily to horizontal magnetic field components generated by magnetic beads, while being relatively insensitive to the vertical magnetic field components from the generator. This directional selectivity enables compact design without sacrificing interference resistance
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This configuration reduces interference from the magnetic field line generator, simplifies the sensor structure, and enables more precise detection of biomolecule density or concentration while maintaining a compact device design suitable for handheld biological detectors.
Implementation Method 1
applying an external magnetic field within a specific range, generating an additional magnetic field using a superparamagnetism of the magnetic beads
Implementation Method 2
The magnetic sensor is disposed on at least one of the second magnetic field lines, and configured to sense a magnetic field component of the at least one of the second magnetic field lines
Data Source
AI summary
A biomolecule magnetic sensor configured to sense magnetic beads attached with biomolecules includes an adsorption pad, a magnetic field line generator and at least one magnetic sensor. The adsorption pad is configured to adsorb the magnetic beads. The magnetic field line generator is configured to generate a plurality of first magnetic field lines, and at least one of the first magnetic field lines passes through the magnetic beads along a first direction to induce a plurality of second magnetic field lines, wherein the magnetic field line generator is disposed between the adsorption pad and the magnetic sensor in the first direction. The magnetic sensor is configured to sense a magnetic field component of at least one of the second magnetic field lines in a second direction. A second shift is provided between the magnetic sensor and the adsorption pad in the second direction.


