8-Channel Biopotential Amplifier With PMOS Noise Reduction

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Solution Overview

Problem

Current neural signal acquisition systems suffer from high noise levels, particularly in applications like EEG and ENG, due to thermal and flicker noise, which limits their effectiveness and can lead to electrode corrosion and power consumption issues.

Innovation Solution

A low-noise amplifier design using PMOS input transistors with optimal transistor size and power management, combined with a fully-differential telescopic architecture and a capacitance multiplier, reduces input noise to sub-μVRMS levels and allows for variable frequency response.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional amplifiers are used in neural signal acquisition systems, then the system can operate with standard power consumption and bandwidth, but the noise level increases to 4 μVRMS or higher, which is unacceptable for EEG and ENG applications

Engineering Contradiction:
Improvenoise levelVSAvoidpower consumption
Core Design Contradiction:
Measurement precisionVSUse of energy by moving object

Solution Approach 1:

The patent changes the fundamental parameters of the amplifier by using PMOS transistors instead of conventional NMOS or BJT, optimizing transistor dimensions (W/L ratios), and adjusting bias currents to achieve sub-μVRMS noise levels. The capacitance multiplier parameter is tuned to extend bandwidth while maintaining low noise, resolving the contradiction between measurement precision and power consumption.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs a composite transistor architecture combining PMOS input stage with capacitance multiplier circuitry and telescopic amplification stages. This composite structure integrates multiple functions (noise reduction, bandwidth extension, gain) into a unified low-power design, achieving 0.693 μVRMS noise while consuming only 250 μA.

Inventive Principle:
Principle #40Composite materials

2Adaptability or versatility

If amplifier bandwidth is increased to capture wider frequency ranges of bioelectric signals, then the system can record more signal types, but the noise level and power consumption increase

Engineering Contradiction:
Improvefrequency rangeVSAvoidnoise level
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent implements a dynamic capacitance multiplier that can be tuned to extend the upper bandwidth limit of the amplifier. By dynamically adjusting the capacitance multiplication factor, the system adapts its frequency response to match different recording requirements (EEG, ECG, EMG, ENG) while maintaining low noise performance across the extended bandwidth.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The low-noise amplifier design serves multiple functions: it amplifies bioelectric signals, filters noise, extends bandwidth via capacitance multiplication, and provides variable gain. This universal design captures diverse signal types (brain, heart, muscle, nerve) with a single circuit architecture, achieving adaptability without sacrificing noise performance.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Measurement precision

If BJT transistors are used to reduce flicker noise, then the input noise decreases to 300 nVRMS, but residual DC current of 20 nA causes electrode corrosion over time

Engineering Contradiction:
Improveinput noiseVSAvoidelectrode stability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent uses PMOS transistors with carefully optimized dimensions and biasing to achieve low noise without the corrosion problem of BJT. The design accepts slightly higher flicker noise compared to BJT but eliminates the harmful DC current, extending electrode lifetime. The telescopic architecture and capacitance multiplier compensate for any noise penalty, maintaining sub-μVRMS performance.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

4Measurement precision

If the amplifier gain is increased to improve signal detection, then weak bioelectric signals can be detected, but the bandwidth decreases and noise may be amplified

Engineering Contradiction:
Improvesignal detection capabilityVSAvoidbandwidth
Core Design Contradiction:
Measurement precisionVSSpeed

Solution Approach 1:

The patent segments the amplification function into multiple stages: a low-noise PMOS input stage for signal acquisition, a telescopic amplification stage for gain, and a capacitance multiplier stage for bandwidth extension. This segmentation allows each stage to be optimized independently, achieving high gain (for weak signal detection) while maintaining wide bandwidth through the capacitance multiplication effect.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS11123000B2Digital biopotential acquisition system having 8 channels
Publication Date: 2021.09.21 NEUROLOOP
  • US11123000B2 patent drawing
  • US11123000B2 patent drawing
  • US11123000B2 patent drawing

AI summary

A biocompatible recording system includes a number of input channels for acquiring electronic information from the neural system of a living being. The recording system includes a preamplifier and further amplifier stages. An input of a second amplifier stage is coupled to an output of the preamplifier. A low-pass filter having a capacitance multiplier is connected to the second amplifier stage. The preamplifier of the recording system is designed using P-MOS technology.