Pre-Assembled Filtration Test Setup for Bioprocess Sensor Integration
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Solution Overview
Problem
Existing bioprocess engineering filtration test systems require complex manual assembly and connection of numerous components, including sensors, filters, and fluidic and electrical connections, which complicates handling and setup.
Innovation Solution
The system is pre-configured with pre-assembled components and integrated circuits, including filters, valves, and sensors, to simplify setup and reduce the number of manual assembly steps, with options for single-use disposable components and magnetic or force-locking fixation, and includes pre-configured data receiving instruments for sensor data processing and control.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If manual assembly and connection of numerous components is required, then the system can be highly customizable and adaptable, but the handling and setup become complicated and time-consuming
Solution Approach 1:
The filtration test system is divided into modular components (filtration test section, data receiving instrument, sensors, filters, valves) that can be independently selected and pre-assembled. This segmentation allows the system to be customized for different filtration tests while reducing the complexity of manual assembly, as each module can be prepared separately and then easily integrated.
Solution Approach 2:
Components such as the filtration test section, sensors, filters, and valves can be pre-assembled into complete test units before actual use. This preliminary assembly reduces the complexity of on-site setup and handling, while still allowing customization by selecting different pre-assembled units for specific filtration test requirements.
2Adaptability or versatility
If numerous components require manual connection, then the system can be flexible and adaptable to different test requirements, but the setup time and complexity increase
Solution Approach 1:
The filtration test section and associated components are pre-assembled into complete test units that are ready for immediate use. This preliminary preparation significantly reduces setup time while maintaining adaptability, as different pre-assembled units can be selected based on specific test requirements without requiring time-consuming manual assembly.
Solution Approach 2:
The pre-assembled filtration test section is designed to be universally applicable to different filtration test configurations. By integrating multiple functions (filtration, sensing, valve control, data acquisition) into a single pre-assembled unit, the system maintains adaptability to various test requirements while eliminating the need for time-consuming manual connection of numerous components.
3Adaptability or versatility
If multiple manual connections are required, then the system can be customized for specific tests, but the risk of contamination and assembly errors increases
Solution Approach 1:
The filtration test section and components are pre-assembled in a controlled manufacturing environment where contamination risks are minimized. This preliminary assembly ensures proper connections and reduces the opportunity for contamination or assembly errors during actual test setup, while still allowing customization through selection of different pre-assembled units.
Solution Approach 2:
The filtration test section can be designed as a disposable single-use component that is pre-assembled and sealed. This eliminates the need for repeated manual connections and cleaning, thereby reducing contamination risk and assembly errors while maintaining the ability to customize by selecting different disposable test sections for specific filtration tests.
Data Source
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AI summary
The invention relates to a bioprocess engineering, in particular biopharmaceutical, filtration test system for filtering a liquid test medium (M) within a filtration test in a filtration test section (2) of the filtration test system (1), which leads from a feed container (3) for receiving the test medium (M) to be filtered to a fluid outlet (4) for the filtered test medium (F), wherein the filtration test system (1) is configured to acquire sensor data as test data for at least one filter (6) during the filtration test, on the basis of which the filter of a target system can be selected and/or dimensioned according to predetermined scaling criteria. It is proposed that the filtration test system (1) be at least partially pre-configured in terms of programming and/or circuitry, at least partially in terms of fluid technology, and/or at least partially in terms of sensors.