Biopsy Capsule and Nested Tube Design for Multi-Sample Collection

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Solution Overview

Problem

Biopsy procedures are lengthy and cumbersome when multiple tissue samples are needed, especially from difficult-to-access locations, as existing devices require withdrawal and reintroduction for each sample.

Innovation Solution

A medical device with an outer tube and inner tube system, featuring a movable end effector and capsules, allows for the collection and storage of multiple tissue samples without complete withdrawal, using negative pressure and actuation mechanisms to capture and store samples within the capsules.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If existing biopsy devices are used to collect multiple tissue samples, then tissue samples can be obtained for analysis, but the procedure becomes lengthy and cumbersome requiring repeated withdrawal and reintroduction of instruments

Engineering Contradiction:
Improvenumber of tissue samples collectedVSAvoidprocedure duration
Core Design Contradiction:
Quantity of substanceVSLoss of time

Solution Approach 1:

The device divides the biopsy collection system into separate functional modules: an outer tube that remains in place, an inner tube that moves to access different locations, multiple capsules for storing different samples, and an end effector for tissue capture. This segmentation allows the outer tube to stay positioned while the inner tube and capsules are exchanged or repositioned to collect multiple samples without complete device withdrawal.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The device employs a nested structure where the inner tube is positioned within the outer tube, and capsules are positioned within the inner tube. This nesting allows the smaller components to be moved or exchanged independently while the larger outer tube remains stationary, enabling multiple sample collections without removing the entire device from the body.

Inventive Principle:
Principle #7Nested doll (Nesting)

2Adaptability or versatility

If instruments are introduced through the working channel of a scope to obtain tissue samples, then biopsy samples can be collected, but it becomes cumbersome to access deep or difficult-to-reach locations for multiple samples

Engineering Contradiction:
Improveaccess to difficult-to-reach locationsVSAvoidease of sample collection
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The device incorporates dynamic components including the movable inner tube that can be extended or retracted relative to the outer tube, and the end effector that can expand and contract to capture tissue. This dynamic design allows the operator to access difficult-to-reach locations by extending the inner tube while maintaining easy operation through simple extension and retraction movements.

Inventive Principle:
Principle #15Dynamics

3Quantity of substance

If multiple tissue samples are collected using traditional methods, then comprehensive tissue analysis is possible, but the complexity of withdrawing and reintroducing instruments increases

Engineering Contradiction:
Improvenumber of tissue samplesVSAvoidinstrument manipulation complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The device merges multiple sample collection capabilities into a single integrated system. The outer tube, inner tube, multiple capsules, and end effector work together as one unit, allowing multiple samples to be collected sequentially or simultaneously without requiring separate instrument introductions. This merging reduces the complexity of instrument manipulation while maintaining the ability to collect comprehensive tissue samples.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Facilitates efficient collection of multiple tissue samples from various body locations without repeated device withdrawal, reducing procedure duration and simplifying access to hard-to-reach sites.

Implementation Method 1

A medical device with an outer tube and inner tube system, featuring a movable end effector and capsules, allows for the collection and storage of multiple tissue samples without complete withdrawal, using negative pressure and actuation mechanisms to capture and store samples within the capsules.

Methodology Applied
Scientific EffectNegative pressure: Suction

Data Source

PatentUS20260041412A1Medical devices, systems, and related methods for collecting tissue
Publication Date: 2026.02.12 BOSTON SCIENTIFIC SCIMED INC
  • US20260041412A1 patent drawing
  • US20260041412A1 patent drawing
  • US20260041412A1 patent drawing

AI summary

A medical device includes an outer tube defining a lumen, an inner tube movable within the lumen of the outer tube and an end effector at a distal end of the inner tube. The end effector retracts to capture one or more tissue samples. A capsule is positioned within a distal portion of the inner tube. The capsule includes a proximal opening and a distal opening for receiving the one or more tissue samples.