Disposable Condenser Bag With Filter Heating for Bioreactor Moisture Control

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Solution Overview

Problem

Current condenser designs for bioreactors are complex, costly, and not truly disposable, with inefficiencies in moisture removal, heat management, and flexibility, leading to reduced cooling effectiveness and clogging issues in filters.

Innovation Solution

A disposable bioreactor condenser system using a thermoelectric cooling device integrated with a flexible, nonporous condenser bag that condenses moisture from gas streams, allowing for separate cooling and heating functions and efficient condensate collection, utilizing a mesh to enhance condensation and turbulence.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Area of stationary object

If multiple ducts are used to increase condenser surface area, then the cooling surface area is improved, but the gas velocity increases and residence time decreases, reducing overall cooling effectiveness

Engineering Contradiction:
Improvecondenser surface areaVSAvoidcooling effectiveness
Core Design Contradiction:
Area of stationary objectVSReliability

Solution Approach 1:

The patent transitions from a multi-duct three-dimensional structure to a two-dimensional flat bag structure with internal mesh. This dimensional change allows the gas to flow across a large surface area without constraining it to narrow ducts, maintaining low velocity while maximizing contact area for condensation.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The patent uses a flexible flat bag structure instead of rigid multi-duct construction. The bag can be easily manufactured and disposed of, while the internal mesh provides the necessary surface area for condensation without creating high-velocity flow paths.

Inventive Principle:
Principle #30Flexible shells and thin films

2Device complexity

If cooling zone and heating zone are integrated in the same condenser assembly, then space is saved, but the flexibility to manipulate the two functions independently is reduced

Engineering Contradiction:
Improvecondenser assembly structureVSAvoidfunctional manipulation flexibility
Core Design Contradiction:
Device complexityVSAdaptability or versatility

Solution Approach 1:

The patent separates the cooling function (condenser bag with mesh) from the heating function (filter heater). The cooling zone handles moisture condensation while the heating zone prevents filter clogging, allowing each function to be optimized and controlled independently without structural integration constraints.

Inventive Principle:
Principle #1Segmentation

3Reliability

If heat is removed from exhaust gas and discarded to the environment, then the condensing function is achieved, but energy is wasted

Engineering Contradiction:
Improvecondensing functionVSAvoidheat energy
Core Design Contradiction:
ReliabilityVSLoss of energy

Solution Approach 1:

The patent converts the waste heat removed during condensation into a useful resource by directing it to the filter heater. This prevents filter clogging while utilizing energy that would otherwise be discarded, transforming a harmful waste product into a beneficial heating source.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

4Reliability

If prior art condenser designs with multiple functional areas are used, then condensation and heating functions are achieved, but the assembly becomes complex and costly requiring special tooling

Engineering Contradiction:
Improvecondensation and heating functionsVSAvoidassembly complexity and cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent divides the system into separate functional components: a simple flat bag for condensation and a separate heater for filter protection. This segmentation allows each component to be manufactured using standard, cost-effective processes without requiring complex integrated tooling or specialized assembly procedures.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively reduces moisture content in gas streams, preventing filter clogging, optimizing heat utilization, and providing a cost-effective, flexible solution for bioreactor applications.

Implementation Method 1

cooling the at least one portion of the outer wall surface of the condenser container, thereby to condense moisture in the moist gas stream

Methodology Applied
Scientific EffectCondensation: Condensation

Implementation Method 2

cooling device in contact with at least one portion of the outer wall surface of the condenser container and arranged to cool the at least one portion

Methodology Applied
Scientific EffectHeat transfer: Conduction (thermal)

Data Source

PatentUS9499781B2Disposable bioreactor condenser bag and filter heater
Publication Date: 2016.11.22 GLOBAL LIFE SCIENCES SOLUTIONS USA LLC
  • US9499781B2 patent drawing
  • US9499781B2 patent drawing
  • US9499781B2 patent drawing

AI summary

Disclosed herein is a system and method for condensing moisture in a moist gas stream entering a bioreactor or leaving a bioreactor, forming a dry gas stream for entering or leaving the bioreactor.