Graphical User Interface for Hollow Fiber Bioreactor Cell Expansion Configuration

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Solution Overview

Problem

Current cell expansion systems lack user-friendly configuration and customization options, making it difficult for operators to efficiently set up and manage protocols for growing and harvesting cells in hollow fiber bioreactors.

Innovation Solution

A processor-implemented method and system that utilizes a graphical user interface (GUI) to configure settings, protocols, and display settings, allowing users to select and configure settings through diagram views and data entry pads, enabling customization of cell expansion processes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a graphical user interface with diagram views and data entry pads is implemented, then ease of operation is improved, but device complexity increases

Engineering Contradiction:
Improveease of configurationVSAvoidsystem complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

A graphical user interface acts as an intermediary layer between the operator and the complex bioreactor control system. The GUI provides diagram views that visually represent system components and their interconnections, along with data entry pads that simplify parameter input. This mediator translates complex control functions into user-friendly visual interactions, improving ease of operation while managing system complexity through software abstraction.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If configurable protocol settings are provided through the user interface, then adaptability is improved, but device complexity increases

Engineering Contradiction:
Improveprotocol customizationVSAvoidconfiguration complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system implements dynamic configuration capabilities where protocol settings can be adjusted and customized through the graphical user interface. The diagram views display configurable parameters that can be modified in real-time, allowing the system to adapt to different cell expansion requirements. This dynamic approach enables versatile protocol customization while managing complexity through visual guidance and structured parameter organization.

Inventive Principle:
Principle #15Dynamics

3Ease of operation

If visual diagram views with enabled graphical user interface elements are provided, then ease of operation is improved, but manufacturing precision requirements increase

Engineering Contradiction:
Improveease of configurationVSAvoidinterface rendering precision
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The graphical user interface employs visual indicators such as color-coded enabled and disabled graphical user interface elements in the diagram views. Enabled parameters are displayed with visual cues (such as color or highlighting) to distinguish them from non-configurable parameters. This visual differentiation improves ease of operation by guiding users to appropriate configuration options while managing rendering precision requirements through standardized visual element design.

Inventive Principle:
Principle #32Color changes

Data Source

PatentUS11773363B2Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
Publication Date: 2023.10.03 TERUMO BCT INC
  • US11773363B2 patent drawing
  • US11773363B2 patent drawing
  • US11773363B2 patent drawing

AI summary

Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.