Bioreactor Impeller Blades With Liquid-Driven Unfolding

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Solution Overview

Problem

Existing impeller systems for bioreactors have blades that occupy significant space in the collapsed state and require complex mechanical systems to transition to the expanded position for agitation, risking damage to the flexible container.

Innovation Solution

The impeller system features blades that are aligned non-axisymmetrically in the collapsed state, allowing them to occupy less space and transition to an axisymmetric position due to liquid resistance during agitation, eliminating the need for complex mechanical systems.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Volume of moving object

If foldable blades are used in the impeller system, then the blades can be collapsed to reduce space during transportation, but the blades still occupy significant space around the drive line in the collapsed state

Engineering Contradiction:
Improvespace occupied by blades in collapsed stateVSAvoidtransition mechanism complexity
Core Design Contradiction:
Volume of moving objectVSEase of operation

Solution Approach 1:

The patent applies asymmetry by positioning the impeller blades in a non-axisymmetric collapsed state rather than a symmetric folded configuration. The blades are arranged at different radial distances from the drive shaft, with at least one blade positioned closer to the drive shaft than others, creating an asymmetric compact arrangement that minimizes space occupation while eliminating the need for complex mechanical transition systems.

Inventive Principle:
Principle #4Asymmetry

Solution Approach 2:

The patent implements dynamics by allowing the blades to transition from collapsed to expanded state through rotation along the circumference of the drive shaft. This dynamic transition is enabled by the asymmetric positioning, which allows blades to naturally unfold into their operational axisymmetric configuration through rotational movement driven by liquid resistance during agitation, without requiring additional mechanical unfolding mechanisms.

Inventive Principle:
Principle #15Dynamics

2Reliability

If complex mechanical systems are used to unfold the blades to the expanded position, then the blades can transition to the axisymmetric position for agitation, but the system becomes more complex and risks damaging the flexible container

Engineering Contradiction:
Improverisk of damage to flexible containerVSAvoidmechanical system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies self-service by enabling the blades to automatically transition from the collapsed to the expanded state through their own interaction with the liquid medium. During agitation, liquid resistance acts on the asymmetrically positioned blades, naturally driving them to rotate into their axisymmetric operational configuration without requiring external mechanical assistance. This self-activating mechanism eliminates complex unfolding systems and reduces the risk of container damage.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces complex mechanical unfolding systems with a fluid-dynamics-based transition mechanism. Instead of using motors, linkages, or other mechanical devices to unfold the blades, the system relies on the hydrodynamic forces generated during liquid agitation to naturally position the blades in their operational configuration. This substitution of mechanical systems with fluid-based actuation simplifies the overall system and improves reliability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Volume of moving object

If blades are positioned axisymmetrically around the drive shaft in the collapsed state, then the agitation performance is optimized, but the space occupation around the drive shaft increases

Engineering Contradiction:
Improvespace occupied around drive shaftVSAvoidagitation performance
Core Design Contradiction:
Volume of moving objectVSProductivity

Solution Approach 1:

The patent uses dynamics to create a system that exists in two distinct states: a non-axisymmetric collapsed state for compact storage and transportation, and an axisymmetric expanded state for optimal agitation performance. The transition between these states is dynamic and automatic, triggered by the liquid agitation process itself. This allows the system to achieve both compactness when not in use and optimal performance when operational.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent applies parameter changes by altering the spatial arrangement of the blades between collapsed and expanded states. In the collapsed state, blades are positioned at asymmetric radial distances with reduced angular separation. During agitation, parameters such as blade angular position, radial distance, and orientation change as blades rotate into their axisymmetric operational configuration, optimizing agitation performance while maintaining compact storage capability.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This design reduces space occupation, minimizes damage to the flexible container, and simplifies the transition process, enhancing transportation and reliability while reducing the risk of puncturing.

Implementation Method 1

at least one of the at least two impeller blades transitions from the collapsed state to the un-collapsed state by rotating along a circumference of the drive shaft due to resistance from a liquid in the bioreactor when agitation is performed

Methodology Applied
Scientific EffectHydrodynamic resistance: Drag

Data Source

PatentUS20260022319A1Impeller system for use with a bioreactor
Publication Date: 2026.01.22 APPLIKON BIOTECH BV
  • US20260022319A1 patent drawing
  • US20260022319A1 patent drawing
  • US20260022319A1 patent drawing

AI summary

The disclosure relates to an impeller system (1) for use with a bioreactor (2), having a drive shaft (3) configured for being rotated in a rotational direction (R) around a longitudinal axis (X) of the drive shaft by a drive motor (4) of the bioreactor; at least two impeller blades (5) connected to the drive shaft, configured for being rotated along with the drive shaft when the drive shaft is rotated, wherein the at least two impeller blades are configured for transitioning from a collapsed state to an un-collapsed state, for performing agitation. At least one of the at least two impeller blades transitions from the collapsed state to the un-collapsed state by rotating along a circumference (6) of the drive shaft due to resistance from a liquid (7) in the bioreactor when agitation is performed.