Bioreactor Semipermeable Membrane for Continuous Metabolite Production

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current methods for producing hydrogen gas, such as Natural Gas Reforming, Electrolysis, and Light-Bacteria-Direct Metabolic Process, face inefficiencies and environmental concerns, with bioreactor designs unable to be scaled up for commercial production due to disruption of microorganisms and low hydrogen yield rates.

Innovation Solution

A bioreactor system utilizing a semipermeable membrane to contain microorganisms like cyanobacteria, which allows for continuous substrate supply and metabolite production without disturbing the microorganisms, using renewable energy sources and optimizing metabolic pathways for enhanced hydrogen gas and metabolite production.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of stationary object

If bioreactor is designed to allow replenishment of substrate, then continuous metabolite production is enabled, but microorganisms must be disturbed or removed which reduces productivity

Engineering Contradiction:
Improvecontinuous operation durationVSAvoidmetabolite production rate
Core Design Contradiction:
Duration of action of stationary objectVSProductivity

Solution Approach 1:

The bioreactor is segmented into two distinct compartments: a first compartment containing the microorganisms and a second compartment for substrate and metabolite flow. This segmentation allows substrate replenishment and metabolite removal without disturbing the microorganisms in the first compartment, thus maintaining continuous operation without productivity loss.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A semipermeable membrane acts as an intermediary between the first compartment (microorganisms) and the second compartment (substrate/metabolite flow). This membrane enables selective transport of substrates and metabolites while physically isolating the microorganisms from disturbance during replenishment operations.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Quantity of substance

If bioreactor is designed for commercial scale production, then hydrogen gas yield increases, but system complexity and operational disruption increase

Engineering Contradiction:
Improvehydrogen gas yieldVSAvoidbioreactor design complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The bioreactor system is divided into functional segments: a first compartment for microbial containment and metabolism, and a second compartment for substrate feeding and metabolite collection. This modular segmentation enables scalable design for commercial production while maintaining operational simplicity through clear functional separation.

Inventive Principle:
Principle #1Segmentation

3Productivity

If conventional hydrogen production methods are used, then high hydrogen yield is achieved, but environmental harm and resource depletion occur

Engineering Contradiction:
Improvehydrogen production efficiencyVSAvoidenvironmental impact
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The system employs microorganisms that autonomously convert substrates into hydrogen gas and other metabolites through natural metabolic processes. This self-service mechanism eliminates the need for energy-intensive industrial processes like natural gas reforming or electrolysis, thereby reducing environmental harm and resource depletion while maintaining hydrogen production efficiency.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The bioreactor system increases nutrient consumption and extends metabolism duration, achieving higher metabolite production with reduced nutrient inputs, energy, and waste, facilitating scalable commercial hydrogen gas production.

Implementation Method 1

a first compartment separated from a second compartment by a semipermeable membrane

Methodology Applied
Scientific EffectSemipermeable membrane filtration: Semipermeable Membrane

Implementation Method 2

microorganisms activated by either or both a substrate and light

Methodology Applied
Scientific EffectPhotosynthesis: Photosynthesis

Data Source

PatentUS20240034967A1Device for producing metabolites
Publication Date: 2024.02.01 GENEREN LABS INC
  • US20240034967A1 patent drawing
  • US20240034967A1 patent drawing
  • US20240034967A1 patent drawing

AI summary

A bioreactor for producing hydrogen gas and metabolites and methods for making and using the same. The bioreactor comprises a main reactor chamber, a semipermeable membrane, a sleeve, microorganism, such as cyanobacteria, for producing hydrogen gas and metabolites, a power supply, a substrate medium, a heating member, a plurality of tubing members, a collection reservoir, a pressure-sealed connecter member, a metabolite purifying filter member, a light source, and an agitator. The bioreactor utilizes light, fermentation, and other metabolic processes for the production of metabolites, derived from various microorganisms contained within the bioreactor through respective metabolic pathways.