Bioresorbable Foaming Tissue Dressing for Wound Conformity
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current wound treatment methods using reduced pressure therapy face challenges in obtaining a proper fit with porous pads that need frequent replacement, potentially removing healthy tissue and not being biodegradable, and lacking sufficient porosity for effective fluid channeling.
Innovation Solution
A bioabsorbable tissue dressing composed of a gas-forming porogen and a gel or gel-forming solution that can be poured or injected onto a wound, conforming to its shape and providing sufficient porosity for reduced pressure treatment, which includes a mixture of a carbonate salt and an acid to create pores and a gel-forming solution made from bioresorbable materials.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a porous pad is used for reduced pressure therapy, then fluid channeling and pressure distribution are improved, but the pad requires frequent removal and replacement which removes healthy tissue
Solution Approach 1:
The patent uses a porous foam material made from a biodegradable polymer matrix that provides the necessary fluid channeling and pressure distribution capabilities. The porosity is achieved through a foaming process that creates interconnected pores, allowing the dressing to function effectively in reduced pressure therapy while being composed of biodegradable materials that eliminate the need for removal.
Solution Approach 2:
The patent employs a biodegradable polymer composition that decomposes naturally in the body over time. This disposable approach eliminates the need for repeated removal and replacement of the dressing, thereby preventing tissue trauma associated with frequent manipulations while maintaining therapeutic effectiveness throughout the degradation period.
2Ease of manufacture
If a biodegradable polymer is formed in advance into a particular shape, then manufacturing is simplified, but it cannot conform to wounds of inconsistent shapes and sizes
Solution Approach 1:
The patent utilizes a two-part room temperature vulcanizing foam system that remains in a liquid or semi-liquid state during application, allowing it to flow and conform to the irregular contours of the wound. Once applied, the foam undergoes in-situ vulcanization to form a solid, porous structure that adapts perfectly to the wound's unique shape and size, eliminating the need for pre-forming while maintaining manufacturing simplicity.
Solution Approach 2:
The patent employs a chemical parameter change approach where the foam material transitions from a liquid state (easy to pour and conform) to a solid state (structurally sound and porous) through a room temperature vulcanization reaction. This phase transition allows the material to be easily applied in liquid form to conform to any wound shape, then solidifies to provide the necessary structural integrity and porosity for reduced pressure therapy.
3Adaptability or versatility
If a foam dressing is poured onto a wound to conform to its shape, then adaptability is improved, but porosity is insufficient for reduced pressure therapy
Solution Approach 1:
The patent incorporates a foaming agent into the polymer composition that generates gas bubbles during the vulcanization process, creating a porous structure within the foam. This controlled foaming ensures sufficient porosity and interconnected pore channels are formed, enabling effective fluid evacuation and pressure distribution while maintaining the foam's ability to conform to the wound's shape and provide structural support for reduced pressure therapy.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The dressing effectively conforms to the wound shape, allows for reduced pressure therapy, and is biodegradable, reducing trauma and the need for frequent dressing changes while promoting tissue growth and healing.
Implementation Method 1
a gas-forming porogen and a gel or gel-forming solution
Implementation Method 2
biodegradable polymer composition that conforms to the exact shape of a wound
Implementation Method 3
delivering the foaming mixture onto the tissue site while the mixture is foaming
Data Source
AI summary
Provided is a flowable bioresorbable tissue dressing comprising a gas-forming porogen and a gel or gel-forming solution. Also provided is kits for preparing the above-described tissue dressing. Further provided are methods of treating a tissue site of a mammal with the above dressing. Also provided is a reduced pressure delivery system for applying a reduced pressure tissue treatment to a tissue site.