Biosensor Abnormal Waveform Detection Circuit

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Solution Overview

Problem

Conventional biosensors experience measurement precision deterioration due to external factors like impacts, sample application issues, and sensor deterioration, leading to abnormal waveforms and inaccurate results.

Innovation Solution

A biosensor measurement system with a second electrode system for abnormality detection, which applies voltage continuously during measurement to monitor and detect abnormal waveforms, allowing for error display and enhanced precision by distinguishing between normal and abnormal measurement conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a conventional single electrode system is used for measurement, then the device complexity is low, but measurement precision deteriorates due to inability to detect abnormal waveforms

Engineering Contradiction:
Improvemeasurement precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The electrode system is segmented into a first electrode system for normal measurement and a second electrode system for abnormality detection. This segmentation allows each electrode system to perform its specific function independently, enabling abnormal waveform detection without interfering with the primary measurement function, thus resolving the contradiction between measurement precision and device complexity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The second electrode system serves multiple purposes: it detects abnormal waveforms during measurement, identifies external factors like impacts, and provides diagnostic information about sensor deterioration. This multi-functionality allows the system to maintain high measurement precision while managing device complexity through shared detection capabilities.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If voltage is applied continuously to detect abnormal waveforms, then measurement precision improves, but energy consumption increases

Engineering Contradiction:
Improvemeasurement precisionVSAvoidenergy consumption
Core Design Contradiction:
Measurement precisionVSUse of energy by moving object

Solution Approach 1:

Voltage is applied to the second electrode system periodically or at specific measurement points rather than continuously throughout the entire measurement process. This periodic voltage application enables abnormal waveform detection when most critical (during target substance measurement) while reducing overall energy consumption compared to continuous monitoring, resolving the contradiction between measurement precision and energy use.

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively eliminates measurement errors caused by impacts and sensor deterioration, significantly improving measurement precision by detecting and correcting abnormal waveforms in real-time.

Implementation Method 1

an oxidation-reduction current value between the counter electrode and the working electrode is measured to determine the quantity of a target substance

Methodology Applied
Scientific EffectOxidation-reduction reaction: Redox Reactions

Implementation Method 2

many of the conventional biosensors are enzyme sensors using enzymes, and an enzyme sensor is configured such that a working electrode and a counter electrode are placed apart from each other with a predetermined interval and contacting a reduced electron carrier that is obtained by a specific reaction between the target substance and the enzyme

Methodology Applied
Scientific EffectEnzyme reaction: Enzyme

Data Source

PatentEP2053388B1Biosensor measuring system and measuring method
Publication Date: 2016.08.31 PANASONIC HEALTHCARE HLDG CO LTD
  • EP2053388B1 patent drawingFigure 1(a)~1(b)
  • EP2053388B1 patent drawingFigure 2(a)~2(c)
  • EP2053388B1 patent drawingFigure 3

AI summary

There is provided a biosensor measurement system which can output a highly-precise measurement result even when an impact such as falling of the sensor occurs or the biosensor is an exposed sensor. An abnormal waveform detection electrode is provided in addition to electrodes for quantitative determination of a target substance. Therefore, when an impact is caused by such as falling of the sensor in a halt period where no voltage is applied in a voltage application algorithm, the abnormal waveform detection electrode can detect the impact. Further, also an exposed sensor can be detected by the abnormal waveform which is detected by the abnormal waveform detection electrode.