Biosensor Multilayer Structure Adhesive Biocompatible Layer

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Solution Overview

Problem

The existing manufacturing process for multilayer biosensors is complex and prone to damage, requiring multiple steps for release film removal and potentially contaminating the reagent with adhesive substances.

Innovation Solution

A simplified multilayer structure for biosensors where the biocompatible layer is directly adhesive, eliminating the need for additional adhesive layers and release films, with a self-adhesive layer that is pressure-sensitive and hydrophilic, allowing for direct deposition of the reagent without intermediate steps.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If additional adhesive layers and release films are used to deposit the biocompatible layer, then the biocompatible layer can be deposited, but the manufacturing process becomes more complex and time-consuming

Engineering Contradiction:
Improvebiocompatible layer depositionVSAvoidmanufacturing process
Core Design Contradiction:
Ease of manufactureVSDevice complexity

Solution Approach 1:

The patent combines the adhesive layer and biocompatible layer into a single integrated biocompatible layer that inherently possesses adhesive properties. This merging eliminates the need for separate adhesive layers and release films, directly reducing manufacturing steps and process complexity while maintaining the functionality of both adhesion and biocompatibility.

Inventive Principle:
Principle #5Merging (Combining)

2Reliability

If release films are used to protect adhesive surfaces, then the adhesive surfaces are protected, but the manufacturing steps increase and release films may be damaged during perforation

Engineering Contradiction:
Improveadhesive surface protectionVSAvoidmanufacturing steps
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent extracts and eliminates the release film component from the manufacturing process. By designing a biocompatible layer with inherent adhesive properties that does not require protection during handling and assembly, the release film step is completely removed, reducing manufacturing complexity and eliminating the risk of release film damage during perforation operations.

Inventive Principle:
Principle #2Taking out (Extraction)

3Strength

If multiple adhesive layers are used, then the biocompatible layer can be securely deposited, but the number of manufacturing steps and potential contamination risks increase

Engineering Contradiction:
Improveadhesion strengthVSAvoidmanufacturing speed
Core Design Contradiction:
StrengthVSProductivity

Solution Approach 1:

The patent merges the adhesive and biocompatible functions into a single layer, eliminating multiple deposition steps. This integration maintains secure adhesion strength while doubling manufacturing speed by removing intermediate steps, directly addressing the productivity bottleneck in the manufacturing process.

Inventive Principle:
Principle #5Merging (Combining)

4Ease of operation

If release films are removed in separate steps, then the adhesive surfaces are exposed, but the manufacturing time increases and the process becomes more error-prone

Engineering Contradiction:
Improveadhesive surface exposureVSAvoidmanufacturing time
Core Design Contradiction:
Ease of operationVSLoss of time

Solution Approach 1:

The patent removes the release film concept entirely from the process. The biocompatible layer is designed to be inherently adhesive without requiring protective films, eliminating the time-consuming release film removal steps and reducing operational complexity, thereby significantly reducing total manufacturing time.

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach reduces the number of manufacturing steps, avoids reagent contamination, and simplifies the production process, making it faster and more cost-effective while maintaining sensitivity and flexibility in the biosensor structure.

Implementation Method 1

a self-adhesive layer deposited on the biocompatible layer

Methodology Applied
Scientific EffectPressure-sensitive adhesion: Adhesive

Implementation Method 2

the biocompatible layer is deposited directly onto the base layer and is adhesive

Methodology Applied
Scientific EffectAdhesion: Adhesive

Data Source

PatentEP4067880A1Multilayer structure for a biosensor, biosensor and method for its manufacture
Publication Date: 2022.10.05 LINXENS HOLDING SAS
  • EP4067880A1 patent drawingFigure 1A~1C
  • EP4067880A1 patent drawingFigure 1D~1E
  • EP4067880A1 patent drawingFigure 2~3

AI summary

The present invention concerns a multilayer structure (2, 102) for a biosensor, comprising a base layer (4, 104), a biocompatible layer (6, 106) comprising a reagent (8, 108) on the base layer (4, 104), a self-adhesive layer (10, 110) on the biocompatible layer (6, 106), such that the reagent (8, 108) is at least partially aligned with a channel (12, 112) formed in the self-adhesive layer (10, 110), and a top layer (14, 114) on the self-adhesive layer (10, 110). According to the present invention, the biocompatible layer (6, 106) is deposited directly onto the base layer (4, 104) and is adhesive. The present invention also concerns a biosensor and a method for the manufacture of such a multilayer structure.