Biosensor Sampling Channel Air Displacement Cleaning

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Solution Overview

Problem

In existing sampling systems, cleaning liquids can mix with samples during the sampling process due to residual presence in the introduction path, potentially contaminating the sample and affecting biosensor accuracy.

Innovation Solution

A sampling system and method that includes a biosensor in the sampling channel, an introduction path for cleaning liquids, and an air introduction path connected to the atmosphere, where air is introduced to push out residual cleaning liquids from the introduction path into the sampling channel, preventing mixing with the sample during subsequent sampling steps.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If cleaning liquid is introduced through the introduction path to clean the biosensor, then the biosensor is cleaned effectively, but cleaning liquid remains in the introduction path and may mix with the sample during subsequent sampling

Engineering Contradiction:
Improvebiosensor cleaning effectivenessVSAvoidcleaning liquid contamination of sample
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

An air column is introduced as an intermediary substance between the cleaning liquid and the sample. The air column acts as a barrier that prevents the cleaning liquid from mixing with the sample while allowing the cleaning liquid to effectively clean the biosensor. This mediator approach resolves the contradiction by adding a separating layer that eliminates the harmful mixing effect.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

Air is introduced into the sampling channel before sample introduction to push out residual cleaning liquid from the introduction path. This preliminary action of removing cleaning liquid remnants prevents contamination of subsequent samples, thereby resolving the contradiction between effective cleaning and preventing contamination.

Inventive Principle:
Principle #10Preliminary action

2Ease of manufacture

If the introduction path is used to introduce cleaning liquid to the biosensor, then the biosensor can be cleaned, but the cleaning liquid remains in the introduction path and connection portion

Engineering Contradiction:
Improvesystem structure simplicityVSAvoidsample measurement accuracy
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

Air serves as an intermediary that pushes out cleaning liquid from the introduction path and connection portion. This simple air pushing mechanism effectively removes cleaning liquid remnants without requiring complex additional structures, thus maintaining ease of manufacture while ensuring measurement precision.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The cleaning liquid is extracted or removed from the introduction path by introducing air that pushes it out into the sampling channel where it can be discarded. This extraction of the harmful substance (cleaning liquid) from the system prevents it from interfering with subsequent sample measurements.

Inventive Principle:
Principle #2Taking out (Extraction)

3Productivity

If multiple sampling steps are performed without air introduction, then the sampling process is continuous and efficient, but cleaning liquid mixes with samples affecting measurement accuracy

Engineering Contradiction:
Improvesampling process efficiencyVSAvoidconcentration measurement accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The sampling process incorporates periodic air introduction steps between sampling operations. This periodic action of introducing air to push out cleaning liquid creates a rhythm of cleaning-removal-sampling that maintains both productivity and measurement precision by preventing contamination while keeping the overall process efficient.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

Air introduction is performed as a preliminary action before each sampling step to ensure the sampling channel is free of cleaning liquid. This preliminary removal of cleaning liquid prevents measurement errors while maintaining continuous efficient operation through rapid sequential steps.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Effectively removes sample attachments from the biosensor and prevents cleaning liquid contamination, ensuring accurate sample measurements by isolating the cleaning liquid from the sample circulation.

Implementation Method 1

air guided from the air introduction path flows into the sampling channel through the introduction path

Methodology Applied
Scientific EffectFluid displacement:

Data Source

PatentUS20230303958A1Sampling System And Sampling Method
Publication Date: 2023.09.28 TERUMO KK
  • US20230303958A1 patent drawing
  • US20230303958A1 patent drawing
  • US20230303958A1 patent drawing

AI summary

A sampling system includes a sensor (for example, a biosensor) that is provided in a sampling channel so as to be in contact with a sample and measures concentrations of predetermined components in the sample, an introduction path that introduces a cleaning liquid to an upstream side of the sensor of the sampling channel, and an air introduction path that is connected to the introduction path and is opened to the atmosphere. The air guided from the air introduction path flows into the sampling channel via the introduction path.