Biosensor Cartridge Assembly for Low-Heat Chip Connection
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Solution Overview
Problem
Conventional biosensors face issues such as inaccurate color-based target material detection, susceptibility to short circuits, protein denaturation due to high-temperature soldering, and high manufacturing costs, along with the need for expensive and bulky measurement devices with poor reproducibility.
Innovation Solution
A biosensor cartridge with a sensor chip and circuit board connected via a connecting member for physical and electrical coupling, housed in a cartridge structure that minimizes chip damage and optimizes specimen containment, using a connection terminal for secure attachment to a diagnostic device without soldering, and a reinforced design to prevent leakage and enhance rigidity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If wire bonding is performed after activation of the biosensor chip, then electrical connection is achieved, but protein denaturation occurs due to high-temperature soldering
Solution Approach 1:
The patent performs wire bonding before activating the biosensor chip, rather than after. This preliminary action allows the electrical connection to be established while the chip is still in its manufacturing state, avoiding the high-temperature soldering process that would denature the protein-based reactants if performed after activation.
Solution Approach 2:
The patent changes the temperature parameter of the connection process by using wire bonding instead of soldering. Wire bonding operates at lower temperatures that do not cause protein denaturation, thereby maintaining the biological functionality of the activated chip while still achieving reliable electrical connection.
2Ease of operation
If the electrode is formed by expansion to extend from the sensor unit, then connection to measurement device is facilitated, but the sensor chip size increases reducing chip yield
Solution Approach 1:
The patent uses wire bonding to establish electrical connections in a different dimensional approach - rather than expanding the electrode area on the chip surface, thin wires are bonded vertically or at angles from existing pad electrodes, achieving connection without increasing the chip's planar footprint.
3Reliability
If direct contact between biosensor chip and measurement device is used, then signal transmission is direct, but external force causes cracks in the chip
Solution Approach 1:
The patent introduces a circuit board as an intermediary component between the biosensor chip and the measurement device. The chip is mounted on the circuit board, which provides mechanical support and distributes external forces, preventing direct transmission of stress to the fragile chip while still enabling signal transmission through the board's electrical traces.
4Ease of operation
If conventional color development method is used for target material detection, then simple visual determination is possible, but detection accuracy varies by user
Solution Approach 1:
The patent replaces the mechanical/visual detection system with an electrical detection system. Instead of relying on human visual interpretation of color changes, the system uses electrical signals generated by the biosensor to detect target materials, eliminating user-dependent variability while maintaining ease of operation through automated electronic readout.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution reduces sensor chip defects, improves reliability, and enables accurate, cost-effective, and portable biosensor systems for rapid disease diagnosis with enhanced reproducibility and reduced manufacturing costs.
Implementation Method 1
the target material is combined (e.g., disposed) in a channel, if an electrochemical reaction occurs or the target material itself has a charge, electrons or holes in the semiconductor structure are accumulated or depleted due to the electric field effect
Implementation Method 2
a plurality of connecting members performing one-to-one connection of connection pads of the circuit board to the source pad, the drain pad, and the gate pad of the sensor chip
Data Source
AI summary
The present disclosure provides a biosensor cartridge comprising a circuit board including a connection terminal configured to be electrically connectable to an external diagnostic device; a sensor chip configured to detect a target material from an applied analysis specimen and transmit an electrical signal generated by reacting with the detected target material to the connection terminal of the circuit board; and a housing configured to accommodate the circuit board and the sensor chip and surround the circuit board and the sensor chip so that the connection terminal is exposed, and an accommodating portion accommodates the analysis specimen and opens the sensor chip's sensor area in which a reactant reacting specifically with the target material is disposed is formed on one surface of the housing. cancan