Biosensor Cartridge Surface Patterning for Accurate Specimen Delivery

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Solution Overview

Problem

Conventional biosensors face challenges in accuracy due to color-based target material detection, which is user-dependent and prone to inaccuracy, and have structural limitations that increase chip size and cost, while also risking short circuits and contamination during specimen handling.

Innovation Solution

A biosensor cartridge with a hyper water-repellent structure and patterned accommodation portion that guides specimens accurately to the sensor area, reducing the need for large specimen volumes and minimizing the risk of short circuits, featuring a sensor chip with a connection terminal and a housing that exposes the sensor area for efficient electrical signal transmission.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If the electrode is extended from the sensor to include the connector, then the structure is simplified, but the sensor chip size increases and chip yield degrades

Engineering Contradiction:
ImprovestructureVSAvoidsensor chip size
Core Design Contradiction:
Device complexityVSArea of stationary object

Solution Approach 1:

The electrode structure is divided into two separate components: a sensor electrode on the sensor chip and a separate connector electrode. This segmentation allows the sensor chip to be smaller while maintaining electrical connection functionality through the separate connector, thus resolving the contradiction between structural simplicity and chip size.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A conductive adhesive layer is introduced as an intermediary between the sensor electrode and the connector electrode. This mediator enables electrical connection without requiring the electrode to be physically extended across the entire chip, allowing the sensor chip to remain compact while achieving the desired electrical connectivity.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If the specimen accommodation area is widened to allow accurate injection, then the specimen can be handled better, but the cartridge area increases and portability degrades

Engineering Contradiction:
Improvespecimen injection accuracyVSAvoidcartridge area
Core Design Contradiction:
Ease of operationVSArea of stationary object

Solution Approach 1:

The accommodation area is designed with localized features including a recessed portion and a protrusion that creates a confined space. This local structural quality provides precise guidance for specimen injection without requiring the entire cartridge to be larger, thus maintaining portability while improving injection accuracy.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The accommodation structure utilizes vertical dimension with a recessed portion going downward into the cartridge body. This dimensional approach allows the specimen to be accurately positioned and injected without expanding the horizontal footprint of the cartridge, preserving portability while enhancing ease of operation.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Ease of manufacture

If the electrode thickness is made very thin for dicing process, then manufacturing is improved, but damage and short circuit risk increase

Engineering Contradiction:
Improvedicing processVSAvoidelectrode integrity
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

A conductive adhesive layer is applied beforehand to protect the thin electrode during the dicing and assembly processes. This cushioning layer prevents mechanical damage to the fragile thin electrode while maintaining electrical conductivity, thus resolving the contradiction between manufacturability and reliability.

Inventive Principle:
Principle #11Beforehand cushioning (Prior cushioning)

Solution Approach 2:

The electrical connection structure is made composite by combining the thin electrode material with a conductive adhesive layer. This composite structure maintains the electrical properties needed for functionality while adding mechanical strength and damage resistance, thus improving reliability without sacrificing ease of manufacture.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The biosensor cartridge provides accurate and reliable detection of target materials with reduced specimen volume requirements, minimizing contamination risks and maintaining portability while enhancing accuracy and cost-effectiveness.

Implementation Method 1

the accommodating portion includes a pattern structure for lowering surface energy

Methodology Applied
Scientific EffectSurface energy reduction: Surface Tension

Implementation Method 2

if an electrochemical reaction occurs or the target material itself has a charge

Methodology Applied
Scientific EffectElectrochemical reaction: Redox Reactions

Implementation Method 3

electrons or holes in the semiconductor structure are accumulated or depleted due to the electric field effect caused by the combination of the probe material and the target material

Methodology Applied
Scientific EffectElectric field effect: Electric Field

Implementation Method 4

transmit an electrical signal generated by reacting with the detected target material to the connection terminal

Methodology Applied
Scientific EffectElectrical signal transmission: Conduction (electrical)

Data Source

PatentUS20230330661A1Biosensor cartridge and biosensor system including same
Publication Date: 2023.10.19 LG ELECTRONICS INC
  • US20230330661A1 patent drawing
  • US20230330661A1 patent drawing
  • US20230330661A1 patent drawing

AI summary

A biosensor cartridge can include a circuit board including a connection terminal electrically connectable to an external diagnostic device; a sensor chip detecting a target material from an applied analysis specimen, having a reactant reacting specifically with the target material, and transmitting an electrical signal generated by reacting with the detected target material to the connection terminal of the circuit board; and a housing accommodating the circuit board and the sensor chip and surround the circuit board and the sensor chip so that the connection terminal is exposed. The housing has an inclined surface dent from an upper surface and forms an accommodating portion that exposes the sensor area of the sensor chip and accommodates the test specimen. Further, the accommodating portion includes a pattern structure for lowering surface energy.