Biosensor Cartridge Segmentation for Compact High-Sensitivity Detection
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Solution Overview
Problem
Current in vitro diagnostic devices are polarized into high-performance, large, and expensive central laboratory devices or low-performance, small, and low-cost on-site devices, lacking technical alternatives that can meet the demands of early diagnosis, preventive treatment, and health monitoring in a decentralized and miniaturized format.
Innovation Solution
A biosensor cartridge with a compartmentalized structure, featuring an electrode unit with multiple electrodes and a compartment unit that separates the space into signal and reaction chambers, allowing for high-sensitivity detection and rapid diagnosis while maintaining a compact design.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Weight of moving object
If a compact on-site diagnostic device is developed, then portability and distribution ease are improved, but detection sensitivity and diagnostic performance deteriorate
Solution Approach 1:
The device is segmented into a compact cartridge containing reaction chambers and a separate reader unit with electrodes. This segmentation allows the reaction components to be miniaturized and portable while the detection electronics can be optimized independently, resolving the contradiction between small size and detection sensitivity
Solution Approach 2:
A connecting electrode serves as an intermediary component that bridges the reaction chamber and signal chamber. This mediator transfers electrochemical signals from the compact reaction area to the detection area, enabling high sensitivity detection while maintaining overall device compactness
2Productivity
If multiple reaction chambers are integrated into a single cartridge, then diagnostic speed and throughput are improved, but device complexity increases
Solution Approach 1:
The cartridge is segmented into N identical reaction chambers that can be standardized and mass-produced. Each chamber follows the same design pattern, which simplifies manufacturing despite having multiple chambers, thereby increasing diagnostic throughput without proportionally increasing complexity
Solution Approach 2:
The cartridge design is universal and can accommodate different types of reactions and detections in each chamber. The standardized interface and compartmentalization allow the same cartridge structure to serve multiple diagnostic functions, improving productivity without linearly increasing design complexity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The biosensor cartridge achieves high sensitivity and rapid diagnostic capabilities through optimized reaction conditions in each chamber, enabling simultaneous testing of multiple samples and improving detection speed, while also allowing for easy distribution and operation with miniaturized equipment.
Implementation Method 1
a biosensor cartridge for detecting a biological material and generating an electrochemiluminescence signal
Data Source
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AI summary
A biosensor cartridge is disclosed. The biosensor cartridge according to an aspect of the present invention is a biosensor cartridge for detecting a biological material and generating an electrochemiluminescence signal, comprising: an electrode unit including a plurality of electrodes; and a compartment unit disposed on the electrode unit to compartmentalize an entire space provided on the electrode unit into a signal chamber and N reaction chambers surrounding the signal chamber; wherein the electrode unit comprises: a first electrode, at least a portion of which is disposed within the reaction chambers; a second electrode, at least a portion of which is disposed within the signal chamber; and N connecting electrodes disposed to electrically couple a chemical reaction within the reaction chamber to the electrochemiluminescence signal generated within the signal chamber.