Biosensor Electrode Segmentation for Blood Component Measurement
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Conventional methods for measuring blood components, such as glucose levels, face challenges in accuracy and reliability due to interference from substances like ascorbic acid and blood cells, leading to insufficient correction of measured values.
Innovation Solution
A method involving a biosensor with multiple electrode systems, where redox reactions are used to measure blood components, blood cells, and interfering substances, allowing for accurate correction of glucose levels by applying voltages to different electrode systems and converting detected currents into quantifiable values.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional single electrode systems are used to measure blood components, then the device complexity is low, but the measurement precision is insufficient due to interference from blood cells and interfering substances
Solution Approach 1:
The sensor is divided into multiple independent electrode systems (first, second, and third electrode systems) with distinct functions. The first electrode system measures blood component, the second measures blood cells, and the third measures interfering substances. This segmentation allows each electrode to be optimized for its specific measurement task, improving overall measurement precision while maintaining manageable device complexity through functional specialization.
Solution Approach 2:
The sensor integrates multiple measurement functions into a single device that can simultaneously measure blood components, blood cells, and interfering substances using different electrode systems. This multi-functionality enables comprehensive correction of measurement values by incorporating data from all electrode systems, thereby improving measurement precision without requiring separate measurement devices.
2Reliability
If multiple electrode systems are added to measure blood cells and interfering substances, then the measurement precision improves, but the device complexity increases
Solution Approach 1:
The sensor is divided into multiple independent electrode systems (first, second, and third electrode systems) with distinct functions. The first electrode system measures blood component, the second measures blood cells, and the third measures interfering substances. This segmentation allows each electrode to be optimized for its specific measurement task, improving overall measurement precision while maintaining manageable device complexity through functional specialization.
Solution Approach 2:
The measurement values from the second and third electrode systems (blood cells and interfering substances) are used to correct and refine the measurement from the first electrode system. This feedback mechanism continuously improves the reliability of the blood component measurement by compensating for interference effects, creating a self-correcting measurement system.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables high-accuracy and high-reliability measurement and correction of blood component levels, improving the precision of glucose monitoring and other blood component analyses.
Implementation Method 1
a redox reaction occurs between a component in the blood and the oxidoreductase so that electrons move to the electrodes via the mediator
Implementation Method 2
electrons move to the electrodes via the mediator
Implementation Method 3
The blood is drawn into the channel of the sensor by capillary action
Data Source
AI summary
The present invention provides a method of measuring a component in blood, by which the amounts of blood cells and an interfering substance can be measured with high accuracy and high reliability and the amount of the component can be corrected accurately based on the amounts of the blood cells and the interfering substance. In a sensor for measuring a blood component, a first working electrode 13 measures a current that flows during a redox reaction of a blood component, a second working electrode 17 measures the amount of blood cells, and a third working electrode 12 measures the amount of an interfering substance. Next, based on the measurement results, the amount of the blood component to be measured is corrected. Thus, more accurate and precise measurement of the amount of the blood component can be realized.