Biosensor Thermal Management via Heat Sinks and Reflectors

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Solution Overview

Problem

Current biosensor technologies face challenges in combining biological and electronic components due to incompatible temperature requirements, leading to high fabrication costs and sensitivity to environmental temperature changes in thermal flow transducer systems.

Innovation Solution

A biosensor apparatus with a housing made of insulating material, heat sinks, and heat reflectors, along with Peltier elements, allows for thermal contact between the biosensor unit and transducer unit, enabling efficient heat management and reduced sensitivity to environmental temperature fluctuations, thus simplifying manufacturing and operation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If electrochemical transducer is used in biosensor, then manufacturing cost is reduced, but sensitivity to environmental temperature changes increases

Engineering Contradiction:
Improvemanufacturing costVSAvoidsensitivity to environmental temperature changes
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The patent introduces an intermediary thermal management system comprising heat sinks, heat reflectors, and Peltier elements that mediate between the biosensor unit and the environment. This intermediary system absorbs and regulates thermal energy, isolating the electrochemical transducer from environmental temperature fluctuations while maintaining the simplicity of electrochemical detection.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the thermal parameters of the system by introducing active cooling elements (Peltier elements) and thermal management structures (heat sinks with specific thermal conductivity values). These parameter changes enable the system to maintain stable operating temperatures despite environmental variations, allowing the use of cost-effective electrochemical transducers.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If thermostatting is used to maintain temperature stability, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvetemperature stabilityVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent segments the thermal management function into distinct components: heat sinks for heat absorption, heat reflectors for thermal isolation, and Peltier elements for active temperature control. This segmentation allows each component to perform its specific function independently, achieving temperature stability without requiring a complex integrated thermostatting system.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent employs disposable or easily replaceable thermal management components that can be manufactured cost-effectively. The heat sinks and Peltier elements are designed to be simple, inexpensive components that provide adequate temperature control without the need for complex, expensive thermostatting equipment.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Manufacturing precision

If high temperature fabrication is used for electronic components, then manufacturing precision is improved, but biological part fabrication becomes incompatible

Engineering Contradiction:
Improveelectronic component precisionVSAvoidcompatibility with biological parts
Core Design Contradiction:
Manufacturing precisionVSAdaptability or versatility

Solution Approach 1:

The patent divides the biosensor system into separate modules: a biosensor unit containing biological components fabricated at low temperatures, and a transducer unit with electronic components fabricated at high temperatures. These segmented modules are then combined through thermal contact interfaces, allowing each part to be manufactured under optimal conditions without compromising the other.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces thermal management interfaces and coupling elements that act as intermediaries between the low-temperature fabricated biological components and high-temperature fabricated electronic components. These intermediaries enable thermal and mechanical coupling while protecting the biological parts from high temperature damage during fabrication and operation.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This design reduces manufacturing complexity and enhances the biosensor's stability and signal-to-noise ratio by minimizing thermal disturbances, allowing for efficient heat transfer and accurate measurements with improved usability and production efficiency.

Implementation Method 1

a pair of Peltier elements thermally attached to said heat sinks, one element on each heat sink, on said facing surfaces

Methodology Applied
Scientific EffectPeltier effect: Peltier Effect

Implementation Method 2

The heat sinks are made of a material with heat capacity and heat diffusivity large enough to absorb and dissipate the heat flow from the enzymatic reaction quickly

Methodology Applied
Scientific EffectHeat sink: Heat Sink

Implementation Method 3

The heat reflectors are made of a material having a surface with very low emissivity and have a generally flat and thin disc shaped structure

Methodology Applied
Scientific EffectThermal radiation reflection: Reflection

Implementation Method 4

a housing consisting of two housing blocks made of a thermally insulating material

Methodology Applied
Scientific EffectThermal insulation: Thermal Insulation

Implementation Method 5

Heat produced by the reaction between substrates in the fluid and enzymes is transmitted via the opposite large walls of the chamber to the respective Peltier element

Methodology Applied
Scientific EffectEnzymatic reaction: Enzyme

Data Source

PatentUS7947223B2Biosensor apparatus for detection of thermal flow
Publication Date: 2011.05.24 SENZIME
  • US7947223B2 patent drawing
  • US7947223B2 patent drawing
  • US7947223B2 patent drawing

AI summary

In general terms the biosensor apparatus according to the invention comprises a housing (5, 6), a pair of heat sinks (11, 12) and a pair of heat reflectors (13, 14) thermally floating relative to the heat sinks, and a pair of Peltier elements (16) attached to and in thermal contact with the heat sinks (11, 12), one element (16) on each heat sink (11, 12). The housing is made of an insulating material, and the heat sinks (11, 12) are made of a material with thermal properties large enough to absorb the heat flow with only a very slight, negligible disturbance in its temperature, to render their envelope surface having a high heat emissivity. The heat reflectors (13, 14) are made of a material having a very low emissivity and have a generally flat and thin disc shaped structure and acts primarily as radiation shields.