Biosensor Light Absorbing Reagent for Mediator Stability
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Solution Overview
Problem
Conventional biosensors degrade quickly when exposed to light, especially after being removed from their containers, leading to inaccurate measurements due to the sensitivity of the reagent mediator to visible light.
Innovation Solution
Incorporating a light effect reducing agent, such as Food Blue No. 1, Food Green No. 3, or Food Yellow No. 4, into the reagent component that absorbs light in the 400 to 500 nm wavelength range, which is distributed more on the surface during drying, thereby protecting the mediator and reducing degradation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a light effect reducing agent is provided to the walls of the holding container, then the biosensor is protected from light degradation while stored, but the biosensor is immediately exposed to light upon removal from the container
Solution Approach 1:
The patent combines the light effect reducing agent with the reagent component itself, merging the protective function into the core functional element. This ensures continuous protection whether the biosensor is stored or in use, eliminating the vulnerability period when removed from the container.
Solution Approach 2:
The reagent component provides its own light protection through the incorporated light effect reducing agent, making the system self-protecting without requiring external container walls or additional protective structures.
2Ease of operation
If the biosensor is left out of the container for extended use, then measurement convenience is improved, but light degradation increases
Solution Approach 1:
By merging the light effect reducing agent into the reagent component, the biosensor maintains protection during extended external use, enabling convenient operation without sacrificing measurement accuracy even when left outside the container.
3Productivity
If multiple biosensors are stored in the same container, then storage efficiency is improved, but repeated removal and exposure causes cumulative degradation
Solution Approach 1:
Each biosensor becomes self-protecting through the light effect reducing agent incorporated into its reagent component, so that repeated removal and exposure during multi-biosensor storage does not cause cumulative degradation to any individual sensor.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The biosensor experiences less degradation from light exposure, maintaining measurement accuracy even when used after being removed from its container, with improved stability and reduced deviation in glucose level measurements.
Implementation Method 1
a substance that absorbs light with a wavelength of 400 to 500 nm
Data Source
AI summary
The present invention relates to a biosensor, and it is an object thereof to suppress degradation by light. A biosensor (2) comprises a blood component measurement working electrode (5), a blood component measurement counter electrode (6), and a reagent component (9). The reagent component (9) is provided near the blood component measurement working electrode (5) and the blood component measurement counter electrode (6). The reagent component (9) includes a mediator, an oxidoreductase, and a substance that absorbs light with a wavelength of 400 to 500 nm. An insulated substrate (4) is provided, on the surface of which is disposed the blood component measurement working electrode (5) and/or the blood component measurement counter electrode (6). The reagent component (9) is disposed on the one or more electrodes on the insulated substrate (4).