Biosensor Test Strip Metal Layer Sintering

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Solution Overview

Problem

Current biosensor test strip manufacturing methods, such as sputtering and laser ablation, are inefficient due to metal wastage and high energy usage, while additive methods like inkjet printing lack detailed features and benefits.

Innovation Solution

A method involving the application of a first layer of copper and a second layer of gold on a substrate, with high-energy broad spectrum light pulses for sintering, and differential curing of reference traces for machine-readable calibration, reducing metal waste and energy consumption.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If sputtering and laser ablation are used to produce metal tracks, then manufacturing precision is improved, but loss of substance and use of energy worsen

Engineering Contradiction:
Improvemetal track accuracyVSAvoidmetal wastage
Core Design Contradiction:
Manufacturing precisionVSLoss of substance

Solution Approach 1:

The patent changes the physical state and application method of metal materials from vapor deposition (sputtering) and subtractive processing (laser ablation) to liquid inkjet printing and thermal sintering. This parameter change enables precise material placement without waste, as metal particles are deposited only where needed in the circuit pattern

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the mechanical sputtering process and laser ablation system with an inkjet printing system that uses digital control to deposit metal particles. This substitution eliminates the need for bulk metal deposition and subsequent removal, achieving both precision and material efficiency

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Manufacturing precision

If sputtering and laser ablation are used to produce metal tracks, then manufacturing precision is improved, but use of energy worsens

Engineering Contradiction:
Improvemetal track accuracyVSAvoidenergy consumption
Core Design Contradiction:
Manufacturing precisionVSUse of energy by stationary object

Solution Approach 1:

The patent changes the energy application method from continuous high-power laser ablation to pulsed low-power thermal sintering. The inkjet-printed metal particles are sintered using brief thermal pulses that fuse particles together with minimal energy input, compared to the sustained high energy required for laser ablation

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs periodic pulsed action for both inkjet deposition and thermal sintering. The inkjet system deposits metal particles in controlled pulses, and the sintering process uses intermittent thermal pulses to fuse particles. This periodic action reduces overall energy consumption compared to continuous laser processing

Inventive Principle:
Principle #19Periodic action

3Loss of substance

If inkjet printing is used to apply metal layers, then loss of substance is reduced, but manufacturing precision worsens

Engineering Contradiction:
Improvemetal wastageVSAvoidelectrode pattern accuracy
Core Design Contradiction:
Loss of substanceVSManufacturing precision

Solution Approach 1:

The patent replaces conventional inkjet printing with a specialized inkjet system capable of depositing metal particles with high precision. The substitution includes using piezoelectric or thermal inkjet technology that can place metal particles in exact positions with controlled droplet sizes, achieving both material efficiency and pattern accuracy

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent applies local quality control by varying inkjet deposition parameters (droplet size, frequency, spacing) according to the specific requirements of different circuit regions. This enables precise metal particle placement in critical areas while optimizing material usage across the entire substrate

Inventive Principle:
Principle #3Local quality

4Manufacturing precision

If high-energy light pulses are used for sintering metal layers, then manufacturing precision is improved, but use of energy worsens

Engineering Contradiction:
Improvemetal layer bondingVSAvoidlight energy consumption
Core Design Contradiction:
Manufacturing precisionVSUse of energy by stationary object

Solution Approach 1:

The patent optimizes the sintering process by changing parameters such as pulse duration, intensity, and wavelength to match the absorption characteristics of metal particles. This enables effective sintering with minimal energy input, as the light parameters are tuned to maximize heating efficiency of the metal particles while minimizing substrate heating

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the accuracy and efficiency of biosensor test strip production by minimizing metal loss and energy usage while enabling machine-readable calibration and lot coding.

Implementation Method 1

sintering said first metal and said second metal at least partially together by exposing them to one or more pulses of a high-energy broad spectrum light

Methodology Applied
Scientific EffectSintering: Sintering

Implementation Method 2

exposing them to one or more pulses of a high-energy broad spectrum light that maintains the temperature of said substrate below a substrate damage temperature

Methodology Applied
Scientific EffectPhotothermal heating: Heating

Data Source

PatentEP2609228B1Biosensor test member and method for making the same
Publication Date: 2019.10.02 F HOFFMANN LA ROCHE & CO AG
  • EP2609228B1 patent drawingFigure 1A-1
  • EP2609228B1 patent drawingFigure 1A-2
  • EP2609228B1 patent drawingFigure 1B

AI summary

A biological test member, and method of making the same, is disclosed with the member including a substrate. The test member has usefulness, for example, in testing a person's blood glucose level. A first layer and a second layer of conductive metal are printed or otherwise applied on the substrate in an electrode pattern. The metal or metals are cured or sintered at a low, non-damaging temperature, such as by applying one or more pulses of a high-energy broad spectrum light. A layer of reagent may be provided on said second metal layer.