Biosensor Cartridge Signal Processing for Multi-Target Diagnosis
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Solution Overview
Problem
Current biosensor technologies face challenges in providing accurate and prompt diagnosis results, especially when dealing with electrical signals below a reference level and in distinguishing between multiple target materials, and they often require complex procedures and specialized knowledge.
Innovation Solution
A biosensor diagnostic device and system that includes an interface for receiving electrical signals from biosensor cartridges, an image reader for capturing code images, a signal processor for processing signals, and a wireless transceiver for transmitting diagnostic information, allowing for accurate diagnosis regardless of signal levels and enabling the detection of multiple target materials using multiple biosensor cartridges.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a strip-type rapid kit with color development is used for target material detection, then the device complexity is reduced and ease of operation is improved, but the measurement precision deteriorates due to inaccurate color conversion and difficulty in visual determination
Solution Approach 1:
The patent replaces the visual color development method with an electrical signal detection system. The biosensor converts the biochemical reaction into an electrical signal that can be objectively measured and processed, eliminating the subjectivity and inaccuracy of visual color assessment while maintaining the simplicity of the testing procedure
Solution Approach 2:
The patent changes the detection parameter from optical color intensity to electrical signal characteristics. By measuring electrical parameters such as current, voltage, or impedance changes in response to target material binding, the system achieves higher precision while keeping the operational interface simple for users
2Measurement precision
If an electrochemical-based biosensor is used to generate electrical signals for target material detection, then the measurement precision is improved, but the device complexity increases due to the importance of electrode resistance and interfacial properties
Solution Approach 1:
The patent integrates the biosensing element, signal transduction mechanism, and signal processing electronics into a unified cartridge system. This merging of components simplifies the overall device architecture by pre-assembling the complex electrochemical interface and electronics into a single replaceable unit, reducing the complexity burden on the main device
Solution Approach 2:
The patent introduces a signal processing unit that acts as an intermediary between the complex electrochemical biosensor and the user interface. This intermediary component handles the complexity of electrode resistance compensation and interfacial property adjustments, presenting a simplified output to the user while maintaining high measurement precision
3Device complexity
If a single biosensor cartridge is used for detection, then the device complexity is reduced, but the adaptability deteriorates as it cannot distinguish between multiple target materials
Solution Approach 1:
The patent divides the detection function into multiple specialized biosensor cartridges, each designed to detect specific target materials. This segmentation allows the system to maintain low device complexity by using simple individual cartridges while achieving high adaptability through the ability to select and combine different cartridge types for different detection needs
4Measurement precision
If the biosensor diagnostic device processes only electrical signals above a reference level, then the measurement precision is improved, but the loss of information increases as signals below the reference level are discarded
Solution Approach 1:
The patent implements dynamic signal processing that adapts the reference level threshold based on the specific application context, target material concentration ranges, and detection requirements. This dynamic adjustment allows the system to maintain measurement precision for strong signals while recovering and utilizing previously discarded weak signals, thereby reducing information loss
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system provides prompt and accurate diagnosis results by processing electrical signals from biosensor cartridges, regardless of signal levels, and can detect multiple target materials using multiple cartridges, enhancing user accessibility and accuracy.
Implementation Method 1
when a target material is combined in a channel, if an electrochemical reaction occurs or the target material itself has a charge, electrons or holes in the semiconductor structure are accumulated or depleted due to the electric field effect
Implementation Method 2
electrons or holes in the semiconductor structure are accumulated or depleted due to the electric field effect caused by the combination of the probe material and the target material
Data Source
AI summary
A biosensor diagnostic device can include an interface configured to receive an electrical signal from a biosensor cartridge in response to being connected to a connection terminal of the biosensor cartridge; an image reader configured to capture a code image on the biosensor cartridge. And a signal processor configured to process a signal received from the interface for generating diagnostic result information. Also, the biosensor diagnostic device can include a wireless transceiver configured to transmit information corresponding to the code image and the diagnostic result information to a server or an external terminal.