Biosensor Strip Code-Recognition Element Automates Calibration
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Solution Overview
Problem
Conventional electrochemical biosensor strips require calibration steps that users often omit or perform incorrectly, leading to inaccurate results, and there is a need to simplify the identification of corresponding biosensing devices for specific strips.
Innovation Solution
Incorporating a code-recognition element on the biosensor strip's base to automatically select the correct calibration code and using length-changeable electrodes to identify the corresponding biosensing device by measuring resistance values, eliminating the need for user calibration and simplifying device-strip matching.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If conventional batch production methods are used for biosensor strips, then production efficiency is improved, but manufacturing precision deteriorates due to variable electrode volumes, enzyme quantities, and other parameters causing batch-to-batch variations
Solution Approach 1:
The patent applies preliminary action by pre-calculating and pre-setting calibration codes that correspond to specific batch parameters before production. Each batch is assigned a unique calibration code that encodes the expected electrode volume, enzyme quantity, and other critical parameters. This allows the calibration to be performed automatically without requiring manual measurement or adjustment during or after production, thus maintaining high productivity while ensuring manufacturing precision through predetermined specifications.
2Manufacturing precision
If manual calibration steps are required for each strip batch, then manufacturing precision is maintained through calibration, but device complexity and ease of operation worsen due to additional user steps that are often omitted or performed incorrectly
Solution Approach 1:
The patent implements self-service by enabling the biosensor strip to perform its own calibration automatically. The calibration code embedded in the strip base automatically identifies the correct calibration parameters when inserted into the meter, and the system automatically executes the calibration without requiring user intervention. This eliminates the complexity of manual calibration steps while maintaining manufacturing precision, as the embedded code ensures accurate calibration for each specific batch.
Solution Approach 2:
The calibration code acts as an intermediary that bridges the gap between the physical strip characteristics and the electronic calibration requirements. This intermediary element automatically translates the batch-specific physical parameters (electrode volume, enzyme quantity) into the appropriate calibration settings, eliminating the need for manual calibration steps while ensuring precision.
3Manufacturing precision
If multiple calibration codes are provided for different batches, then manufacturing precision is maintained, but device complexity increases due to the need to store and select correct calibration codes
Solution Approach 1:
The patent applies segmentation by dividing the calibration information into discrete, batch-specific codes that are embedded in each strip. Instead of managing a large database of calibration codes, the system segments the calibration data into individual strip-level identifiers. This reduces device complexity by eliminating the need for complex code selection and management systems, while maintaining manufacturing precision through batch-specific calibration codes that are automatically applied.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution simplifies the measurement process, reduces calibration errors, decreases production costs, and enhances user convenience by automating calibration and device identification, ensuring accurate results without additional user intervention.
Implementation Method 1
After blood glucose reacts with an enzyme at the electrochemical biosensor strip, electrons release during the forward reaction, and therefore the change of the current flow occurs
Implementation Method 2
using length-changeable electrodes to identify the corresponding biosensing device by measuring resistance values
Data Source
AI summary
The present invention relates to an electrochemical biosensor strip comprising a base which has a front side and a back side, an electrode system on the front side of said base, a code-recognition element on one end of the back side of said base, a cover which is located on said electrode system, and a reaction area which is in touch with said electrode system for a reaction to take place. By forms of said code-recognition element provided in the present invention, a biosensing device will automatically choose a specific set of calibration code corresponding to a particular batch of the electrochemical biosensor strip while coupling to the strip. Hence, the present invention eliminates the calibration step carried out by users and simplifies the measuring procedure, avoiding the inaccurate results due to the omission or improper operation of the calibration step by users. The present invention further relates to a method for identifying a corresponding biosensing device by using a ratio of lengths of each length-changeable area of the strip.