Biosignal-Adaptive Electrical Stimulation for Pain Management
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing implantable electrical stimulation systems lack the ability to dynamically adjust stimulation parameters based on real-time biosignal measurements, which can lead to suboptimal therapeutic outcomes.
Innovation Solution
The system utilizes measured power spectra or signal coherence to modify stimulation parameters, allowing for real-time adjustments based on biosignal analysis.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If implantable electrical stimulation systems deliver fixed stimulation parameters, then device complexity is reduced, but therapeutic efficacy deteriorates due to inability to adapt to real-time biosignal changes
Solution Approach 1:
The system continuously monitors biosignals (such as EMG or EEG) and uses this feedback information to automatically adjust stimulation parameters. The processor analyzes the biosignal characteristics and modifies stimulation delivery in real-time, creating a closed-loop control system that adapts to changing physiological conditions without requiring external intervention.
Solution Approach 2:
The stimulation system performs self-adjustment by automatically analyzing its own operational parameters through biosignal monitoring and autonomously modifying stimulation settings. This eliminates the need for continuous external programming or manual adjustment by healthcare providers, allowing the device to optimize its own performance based on real-time physiological feedback.
2Adaptability or versatility
If implantable electrical stimulation systems continuously monitor biosignals and adjust parameters in real-time, then therapeutic efficacy is improved, but device complexity increases
Solution Approach 1:
The stimulator electrodes serve multiple functions: they both deliver electrical stimulation to the target tissue and detect biosignals for analysis. This multi-functionality reduces the need for separate sensing components, thereby limiting the increase in device complexity while enabling real-time adaptability through the same electrode array used for stimulation.
3Ease of operation
If external programmers are required to adjust therapy delivery, then device complexity is reduced, but ease of operation deteriorates due to need for external device interaction
Solution Approach 1:
The system performs self-adjustment by automatically analyzing its own operational parameters through biosignal monitoring and autonomously modifying stimulation settings. This eliminates the need for continuous external programming or manual adjustment by healthcare providers, allowing the device to optimize its own performance based on real-time physiological feedback.
Data Source
Figure 1
Figure 2
Figure 3A
AI summary
Methods and systems for electrical stimulation can include obtaining a biosignal of the patient; altering at least one stimulation parameter of an electrical stimulation system in response to the biosignal; and delivering an electrical stimulation current to one or more selected electrodes of the electrical stimulation system using the at least one stimulation parameter. In some embodiments, a power spectrum is determined from the biosignal. In some embodiments, the biosignal is at least two different biosignals measured at the same or different locations on the patient and a coherence, correlation, or association between the two biosignal is determined.