Biostimulant Formulation pH Adjustment Chelation

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Solution Overview

Problem

Existing biostimulant compositions face issues with sedimentation and poor storage stability due to the limited solubility of L-Phenylalanine and seaweed extracts, which affect their efficacy in mitigating abiotic stress and enhancing crop productivity.

Innovation Solution

A formulation comprising Ascophyllum nodosum extract, L-Phenylalanine, a surfactant, and a chelating agent, adjusted to a pH above 9, enhances solubility and stability, preventing sedimentation and maintaining biostimulant efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If L-Phenylalanine is used at high concentrations (up to 50 g/L or higher), then biostimulant efficacy is improved, but crystal growth occurs and solubility is reduced

Engineering Contradiction:
Improveconcentration of L-PhenylalanineVSAvoidsolubility and crystal growth
Core Design Contradiction:
Quantity of substanceVSStability of the object's composition

Solution Approach 1:

The patent introduces a chelating agent as an intermediary substance that binds to L-Phenylalanine and prevents crystal formation. The chelating agent acts as a mediator between the high concentration of L-Phenylalanine and the solution stability, allowing high concentrations to be maintained without crystal growth by forming stable complexes.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the chemical parameters of the solution by adjusting pH to above 9 and adding chelating agents. These parameter changes modify the solubility characteristics of L-Phenylalanine, allowing it to remain in solution at high concentrations without crystallizing. The pH adjustment and chelation fundamentally alter the physical-chemical state of L-Phenylalanine in the formulation.

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If seaweed extract is used at high concentrations, then biostimulant efficacy is improved, but sedimentation occurs over time

Engineering Contradiction:
Improveconcentration of seaweed extractVSAvoidstorage stability and sedimentation
Core Design Contradiction:
Quantity of substanceVSStability of the object's composition

Solution Approach 1:

The patent introduces a chelating agent as an intermediary that stabilizes seaweed extract in the formulation. The chelating agent binds to metal ions in the seaweed extract, preventing aggregation and sedimentation. This intermediary substance allows high concentrations of seaweed extract to be maintained while preserving storage stability.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the chemical environment by adjusting pH to above 9 and adding chelating agents. These parameter changes modify the stability characteristics of seaweed extract, preventing sedimentation over time. The alkaline pH and chelation fundamentally alter the physical-chemical state of the seaweed extract, maintaining it in a stable, non-sedimenting form.

Inventive Principle:
Principle #35Parameter changes

3Stability of the object's composition

If pH is adjusted to above 9, then solubility of L-Phenylalanine is improved, but formulation stability may be affected

Engineering Contradiction:
Improvesolubility of L-PhenylalanineVSAvoidformulation stability
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent introduces a chelating agent as an intermediary that stabilizes the formulation at high pH. The chelating agent binds to metal ions that would otherwise catalyze degradation reactions at alkaline pH, thereby stabilizing the formulation. This intermediary substance allows the pH to be adjusted above 9 for improved solubility while preventing formulation degradation.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the chemical parameters by adjusting pH to above 9 and adding chelating agents. These parameter changes are designed to work synergistically: the high pH improves solubility while the chelating agent counteracts potential stability issues. The combined parameter changes achieve both improved solubility and maintained formulation stability.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The formulation achieves high solubility and stability, allowing for effective abiotic stress mitigation and enhanced crop productivity, with synergistic effects observed in field trials.

Implementation Method 1

at least one chelating agent

Methodology Applied
Scientific EffectChelation:

Implementation Method 2

at least one surfactant, more preferably a dispersant

Methodology Applied
Scientific EffectSurfactant action: Surfactant

Implementation Method 3

L-Phenylalanine is only partly soluble in water and susceptible to crystal growth at a concentration of up to 50 g/L or higher in a solution... The pH of the formulation is preferably 8.0 or more, more preferably 9.0 or more, even more preferably 9.5 or more

Methodology Applied
Scientific EffectpH-dependent solubility:

Data Source

PatentEP4573904A1Biostimulant composition and methods of use
Publication Date: 2025.06.25 ACADIAN SEAPLANTS LTD
  • EP4573904A1 patent drawingFigure 1
  • EP4573904A1 patent drawingFigure 2
  • EP4573904A1 patent drawingFigure 3

AI summary

The present invention relates to a plant biostimulant composition comprising: (i) a seaweed, (ii) at least one biostimulant, (iii) at least one surfactant, and (iv) at least one co-formulant wherein said composition has a pH above about 9. Optionally, the composition further comprises at least one agriculturally acceptable carrier and/or additives, such as chelating agents and/or rheological aids. The present invention further relates to methods and uses for drench application of the plant biostimulant composition for mitigating abiotic stress or to manage crop productivity.