Synergistic Antimicrobial Composition BIT Tris Nitro
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Solution Overview
Problem
Commercial antimicrobial compounds often fail to effectively control microorganisms due to weak activity or slow action, especially against certain types of microorganisms, and may be unstable under high temperature and high pH conditions, necessitating the development of combinations with enhanced activity.
Innovation Solution
A synergistic antimicrobial composition comprising 1,2-benzisothiazolin-3-one (BIT) and tris(hydroxymethyl)nitromethane (Tris Nitro) in a weight ratio ranging from 12:1 to 1:12, which provides enhanced microbial control by combining their antimicrobial properties.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If commercial antimicrobial compounds are used at high concentrations, then microbial control effectiveness may improve, but stability under high temperature and high pH conditions deteriorates
Solution Approach 1:
The patent combines two different antimicrobial compounds (BIT and Tris Nitro) into a single composition. This merging allows the formulation to achieve effective microbial control while maintaining stability under challenging conditions (high temperature and high pH), as the compounds work synergistically rather than requiring high concentrations of a single unstable compound
Solution Approach 2:
The invention creates a composite antimicrobial system by formulating BIT and Tris Nitro together in specific weight ratios (1:1 to 1:10). This composite approach enables the composition to provide both effectiveness against microorganisms and stability under high temperature and pH conditions, resolving the contradiction between reliability and stability
2Device complexity
If single antimicrobial compounds are used, then formulation simplicity is maintained, but antimicrobial activity against certain microorganisms is insufficient
Solution Approach 1:
The patent merges two antimicrobial compounds (BIT and Tris Nitro) into a single formulation with a simple weight ratio range (1:1 to 1:10). This combination provides enhanced antimicrobial activity against various microorganisms while maintaining formulation simplicity, as no complex multi-step processes or additional components are required
3Reliability
If higher use concentrations of antimicrobial compounds are applied, then microbial control effectiveness improves, but cost and waste increase
Solution Approach 1:
The patent changes the parameter of compound concentration by using a specific combination of BIT and Tris Nitro in weight ratios from 1:1 to 1:10. This parameter optimization achieves effective microbial control at lower overall concentrations compared to using single compounds at high doses, thereby reducing cost and waste while maintaining reliability
Data Source
AI summary
A synergistic antimicrobial composition containing 1,2-benzisothiazolin-3-one and tris(hydroxymethyl)nitromethane.