Blackberry Leaf Extract for Skin Irritation and Inflammation
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Solution Overview
Problem
There is a need for effective, non-toxic, and cost-efficient agents with natural origins to reduce skin irritation and inflammation, particularly for sensitive skin, which current cosmetic and pharmaceutical agents fail to adequately address, especially in terms of stability, odor, and compatibility.
Innovation Solution
A medicament comprising an alcoholic extract of blackberry leaves, obtained by extracting blackberry leaves with a mixture of alcohols such as ethanol and water, which is decolorized and has a concentration range of 0.00001 to 20 wt.%, demonstrating enhanced skin irritation-reducing and anti-inflammatory properties.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional skin irritation-reducing agents are used, then skin irritation is reduced, but they fail to provide adequate stability, have unpleasant odor, or cause skin incompatibility
Solution Approach 1:
The patent changes the chemical parameters of the extract by using specific alcohol ratios (ethanol/water 3:7) and controlled extraction conditions (temperature 80-100°C, time 2 hours) to optimize the extract's stability, odor profile, and skin compatibility simultaneously
Solution Approach 2:
The patent extracts only the beneficial components from blackberry leaves using alcohol extraction, separating the active ingredients (which provide skin irritation-reducing effects) from unwanted components (odor, instability), thereby achieving improved stability and reduced harmful factors
2Object-generated harmful factors
If natural plant extracts are used to address sensitive skin, then skin compatibility improves, but effectiveness against inflammation is insufficient
Solution Approach 1:
The patent creates a composite extract containing multiple active components from blackberry leaves (polyphenols, flavonoids, vitamins) that work synergistically to provide both skin compatibility and strong anti-inflammatory effectiveness, overcoming the limitation of single-component natural extracts
3Object-affected harmful factors
If current cosmetic agents are used for sensitive skin, then some irritation reduction is achieved, but they fail to adequately address interleukin release and inflammation
Solution Approach 1:
The blackberry leaf extract acts as an intermediary substance that mediates between the skin and inflammatory triggers, specifically inhibiting interleukin release while providing skin irritation reduction, thereby bridging the gap between symptom management and underlying inflammation treatment
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The blackberry leaf extract effectively reduces skin irritation and inflammation, inhibiting interleukin release while maintaining stability and minimal odor, making it suitable for cosmetic and pharmaceutical applications without altering the appearance or scent of formulations.
Implementation Method 1
extracting blackberry leaves with a mixture of alcohols such as ethanol and water
Data Source
Figure 1
AI summary
The present invention concerns the field of plant extracts and their uses, in particular for cosmetic, oral hygiene and pharmaceutical purposes. In particular the invention concerns blackberry leaf extracts and preparations and medicaments containing them, as well as their use to inhibit irritating and inflammatory skin conditions.