Blepharometric Monitoring for Personalized Neurological Event Prediction

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Solution Overview

Problem

Current eyelid movement monitoring systems primarily focus on point-in-time analysis for assessing alertness or drowsiness, which is not ideal as blepharometric data biomarkers can vary significantly across individuals, limiting their effectiveness in predicting neurological conditions or events.

Innovation Solution

A blepharometric data collection and analysis system that enables long-term, individualized data tagging of physiological events and conditions, allowing for subsequent configuration of monitoring hardware to predict future events and conditions, using various environments such as vehicles, computing devices, and medical facilities, and differentiating between voluntary and involuntary eyelid movements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If point-in-time analysis is used for assessing alertness, then immediate assessment capability is improved, but prediction accuracy of neurological conditions deteriorates due to individual variability in blepharometric biomarkers

Engineering Contradiction:
Improveimmediate assessment capabilityVSAvoidprediction accuracy
Core Design Contradiction:
SpeedVSMeasurement precision

Solution Approach 1:

The system performs preliminary actions by collecting and storing blepharometric data over extended periods to establish individualized baseline profiles before neurological events occur. This preliminary data accumulation enables subsequent real-time comparison and prediction, resolving the contradiction between immediate assessment and accurate prediction by preparing personalized reference data in advance.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system transitions from static point-in-time analysis to dynamic longitudinal analysis by continuously collecting blepharometric data and updating individualized profiles over time. This dynamic approach allows the system to adapt to individual variability and improve prediction accuracy while maintaining real-time monitoring capabilities.

Inventive Principle:
Principle #15Dynamics

2Measurement precision

If long-term individualized data collection is implemented, then prediction accuracy of neurological conditions is improved, but system complexity and data management requirements worsen

Engineering Contradiction:
Improveprediction accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system applies local quality by creating individualized personalized profiles for each subject rather than using universal thresholds. Each subject's baseline blepharometric characteristics are uniquely characterized, allowing the system to maintain high prediction accuracy while managing complexity through personalized rather than generalized approaches.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The system implements self-service by automatically establishing baseline profiles from collected data without requiring manual intervention for each subject. The automated baseline establishment and continuous monitoring reduce the burden of data management while maintaining individualized analysis, thereby improving prediction accuracy without proportionally increasing operational complexity.

Inventive Principle:
Principle #25Self-service

3Reliability

If comprehensive blepharometric monitoring is deployed across multiple environments, then data quantity and prediction reliability are improved, but ease of operation and implementation difficulty worsen

Engineering Contradiction:
Improveprediction reliabilityVSAvoidease of implementation
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The system achieves universality by designing a multi-functional platform that operates across diverse environments including clinical settings, home environments, and mobile devices. This universal approach allows comprehensive data collection from multiple sources while maintaining consistent analysis methodologies, thereby improving prediction reliability without requiring separate systems for each environment.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system uses an intermediary centralized data management platform that coordinates data collection across multiple environments and devices. This intermediary layer simplifies operation by providing unified data aggregation and analysis, reducing the complexity of managing multi-environment deployment while maintaining high prediction reliability through comprehensive data collection.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS12159241B2Devices and processing systems configured to enable physiological event prediction based on blepharometric data analysis
Publication Date: 2024.12.03 SDIP HOLDINGS PTY LTD
  • US12159241B2 patent drawing
  • US12159241B2 patent drawing
  • US12159241B2 patent drawing

AI summary

Devices and processing systems are configured to enable physiological event prediction based on blepharometric data analysis. For example, some embodiments provide methods and associated technology that enable retrospective analysis of blepharometric data driving subsequent hardware/software configuration, thereby to provide for personalized and/or generalized biomarker identification.