Blood Analyzer Platelet Mixing Vortex Oscillation
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Solution Overview
Problem
Current blood analyzers face issues with uneven vibration during platelet disaggregation, leading to inaccurate platelet counts due to differential oscillation in sample test tubes, causing either insufficient or excessive vibration that can break red blood cells or fail to fully disaggregate platelets.
Innovation Solution
A blood sample platelet uniform-mixing device featuring a vortex oscillation system with a rotating assembly and vibrating assembly, where the sample test tubes are fixed to rotate and vibrate in a way that ensures uniform blood distribution, utilizing a rotating disc with an adapter and elastic parts to create a vortex shape and enhance vibration uniformity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If the sample test tube is oscillated using a single oscillation method, then the platelets near the side wall can be disaggregated, but the blood sample at the central axis is insufficiently oscillated
Solution Approach 1:
The oscillation process is divided into two distinct phases: vortex oscillation for uniform distribution and wall collision oscillation for disaggregation. This segmentation allows each phase to optimize for its specific function, ensuring both central axis and side wall platelets are effectively processed
Solution Approach 2:
The device implements periodic alternation between vortex oscillation and wall collision oscillation modes. This periodic action ensures that platelets throughout the entire sample volume receive adequate disaggregation treatment over time, improving overall measurement accuracy
2Reliability
If the blood sample near the side wall is oscillated intensely to disaggregate platelets, then platelet disaggregation is improved, but red blood cells are broken into fragments
Solution Approach 1:
The device alternates between gentle vortex oscillation and intense wall collision oscillation in periodic cycles. During vortex phase, red blood cells are protected while platelets begin to separate; during wall collision phase, platelets are disaggregated. This periodic modulation prevents continuous intense oscillation that would cause excessive red blood cell fragmentation
Solution Approach 2:
Vortex oscillation is performed as a preliminary action before wall collision oscillation. This preliminary gentle mixing distributes the blood sample uniformly and positions platelets for effective disaggregation during the subsequent wall collision phase, reducing the intensity and duration of intense oscillation needed
3Measurement precision
If the central axis blood sample is oscillated more to disaggregate platelets, then platelet disaggregation is improved, but the blood sample near the side wall is over-oscillated
Solution Approach 1:
The oscillation process is segmented into vortex oscillation that uniformly affects the entire sample including the central axis, followed by wall collision oscillation that targets the side wall region. This spatial segmentation ensures equitable treatment of different sample regions without over-oscillating any particular area
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution ensures more uniform vibration of the blood sample, effectively disaggregating platelets while minimizing red blood cell breakage, thereby improving the accuracy of platelet counts and reducing the risk of false decreases in platelet count results.
Implementation Method 1
The rotating assembly is used for rotating the fixing assembly and making the blood sample in each of sample test tubes be in a vortex shape
Implementation Method 2
The vibrating assembly is used for vibrating the sample test tubes after the blood sample is in a vortex shape
Data Source
AI summary
A blood sample platelet uniform-mixing device for a blood analyzer includes a vortex oscillation device, the vortex oscillation device includes a fixing assembly, a rotating assembly and a vibrating assembly. The fixing assembly is used for fixing sample test tubes. The rotating assembly includes a rotating motor and a rotating disc. A rotating shaft of the rotating motor is connected with the rotating disc, the rotating disc is matched with the fixing assembly. A central axis of each of the sample test tubes fixed on the fixing assembly deviates from the rotating shaft of the rotating motor. The rotating assembly is used for rotating the fixing assembly and making a blood sample in each of the sample test tubes be in a vortex shape. The vibrating assembly is arranged on the fixing assembly.