Blood Treatment Calcium Control via Feedback Dispensing
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Solution Overview
Problem
Existing methods for extracorporeal blood treatment, such as those using citrate for anticoagulation, lead to calcium loss and require precise calcium replenishment to prevent coagulation, but lack effective methods for determining and controlling the necessary calcium dosage and concentration.
Innovation Solution
A method and apparatus for controlling the extracorporeal blood treatment by detecting and outputting signals to a dispensing device to add calcium to the blood circuit, with a control device and user interface for setting calcium dosage, concentration, and concentration of substituate solutions, ensuring permissible settings are maintained within a defined range to prevent coagulation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If citrate is added to the blood for anticoagulation, then coagulation is prevented, but calcium is lost from the blood
Solution Approach 1:
The control device continuously monitors calcium levels in the extracorporeal blood circuit and automatically adjusts the calcium dispensing rate to compensate for citrate-induced calcium loss, maintaining calcium balance throughout the treatment process
Solution Approach 2:
The system recovers calcium by dispensing calcium-containing solutions into the extracorporeal blood circuit at controlled rates, counteracting the calcium loss caused by citrate anticoagulation and membrane permeation
2Quantity of substance
If calcium is added to the blood to compensate for calcium loss, then calcium balance is maintained, but coagulation may occur if dosage is incorrect
Solution Approach 1:
The control device uses real-time monitoring and feedback control to adjust calcium dispensing rates, ensuring that calcium is replenished at the precise rate needed to maintain balance without causing coagulation
Solution Approach 2:
The system dynamically adjusts calcium dosage parameters (concentration, flow rate, timing) based on treatment mode, blood flow rate, and calculated calcium requirements to maintain optimal calcium levels and prevent coagulation
3Ease of operation
If manual calcium dosage setting is used, then operator control is maintained, but precise calcium balance control is difficult to achieve
Solution Approach 1:
The control device automatically calculates and adjusts calcium dispensing parameters based on treatment conditions, eliminating the need for manual dosage calculations and improving precision while maintaining operator oversight through the user interface
4Device complexity
If calcium dispensing is not controlled, then treatment simplicity is maintained, but calcium loss leads to coagulation
Solution Approach 1:
The control device provides automatic feedback control that monitors calcium levels and treatment parameters, adjusting calcium dispensing in real-time to prevent coagulation while maintaining a user-friendly interface that does not significantly increase operational complexity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution ensures accurate and safe calcium replenishment, preventing coagulation by dynamically adjusting calcium levels based on treatment mode and substituate solutions, thereby maintaining a stable calcium balance during extracorporeal blood treatment.
Implementation Method 1
By adding the citrate, calcium is increasingly permeably transferred through the membrane of the utilized filter
Data Source
AI summary
The present invention relates to a method for controlling or regulating an apparatus for extracorporeally treating blood in an extracorporeal blood circuit while adding citrate and calcium for the purpose of anticoagulation. The apparatus comprises a dispensing device for dispensing a calcium solution into the extracorporeal blood circuit. The method encompasses outputting a signal to the dispensing device for altering a setting of the dispensing device, in which the setting corresponds to or effects an addition of calcium, a calcium dosage, concentration, amount or rate. The method further encompasses defining or altering the signal with regard to a calcium content or a calcium concentration of a substituate solution used in extracorporeally treating the blood, and detecting the range of values of permissible or allowed settings for the calcium introduced or to be introduced into the extracorporeal blood circuit by the dispensing device, particularly its amount, concentration or dosage.