Blood Cassette Pressure Measurement Using Soft Wall Load Sensor
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Solution Overview
Problem
Existing biological component transfer systems face challenges in accurately measuring circuit internal pressure, which is crucial for ensuring proper operation, especially in blood component collection and cell therapy applications.
Innovation Solution
A biological component transfer system with a sheet-shaped device main body featuring a biological fluid line that includes an applied load measurement unit with a soft material wall portion, disposed at a location within the fluid line where only positive pressure acts, allowing for accurate measurement without obstruction from negative pressure and minimizing creep deformation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a pressure measurement system is implemented in a biological fluid line, then circuit internal pressure can be monitored, but measurement accuracy deteriorates due to negative pressure blocking or obstructing the measurement
Solution Approach 1:
The patent applies local quality by creating a specific measurement section in the biological fluid line with different properties than the rest of the line. The measurement section has a softer, more easily deformable wall portion that is specifically designed to respond to positive pressure, while being positioned at a location where only positive pressure acts. This localized differentiation allows accurate measurement without being affected by negative pressure conditions elsewhere in the system.
Solution Approach 2:
The patent implements preliminary action by strategically positioning the measurement section at a specific location within the biological fluid line where only positive pressure occurs during operation. By anticipating the pressure conditions and placing the measurement point in advance at a favorable location, the system prevents negative pressure from affecting the measurement, thus ensuring continuous accurate monitoring.
2Measurement precision
If a soft material wall portion is used in the applied load measurement unit, then pressure measurement sensitivity improves, but measurement accuracy deteriorates due to creep deformation over time
Solution Approach 1:
The patent applies parameter changes by carefully selecting and optimizing the material properties of the wall portion in the measurement section. The soft material is chosen to have appropriate elasticity for detecting positive pressure while maintaining dimensional stability and minimizing creep deformation over time. By adjusting material parameters such as elasticity modulus and viscosity, the system achieves both sensitivity to pressure changes and long-term measurement stability.
3Measurement precision
If the applied load measurement unit is made more easily deformed, then pressure detection sensitivity increases, but measurement reliability decreases due to increased creep deformation
Solution Approach 1:
The patent implements local quality by creating a measurement section with differentiated properties - softer and more easily deformable than the rest of the biological fluid line. This localized softness enhances pressure detection sensitivity at the measurement point while the overall line structure maintains sufficient rigidity to prevent excessive creep deformation, thus balancing sensitivity and reliability.
Solution Approach 2:
The patent applies parameter changes by optimizing the deformation characteristics of the measurement section. The wall portion is designed with specific mechanical parameters that allow it to be more easily deformed for sensitive detection, while controlling the degree of deformation to minimize creep effects over time, thereby maintaining measurement reliability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This configuration enables high-accuracy measurement of circuit internal pressure by preventing obstruction from negative pressure and reducing creep deformation, ensuring reliable operation of the system.
Implementation Method 1
the applied load measurement unit includes a wall portion made of a soft material... since the applied load measurement unit is more easily deformed than the line main body portion, creep deformation of the applied load measurement unit (a reduction in the reaction force of the applied load measurement unit over time) can be suppressed
Data Source
AI summary
A blood component collection cassette of a blood component collection system, which is a biological component transfer system, includes a sheet-shaped cassette main body in which a blood line is formed. The blood line includes a second applied load measurement unit and line main body portions. A separation device includes a second load measurement unit that measures a load applied to a wall portion of the second applied load measurement unit in a cassette mounted state. The second applied load measurement unit is more easily deformed than the line main body portions, and is disposed at a location within the blood line on which only a positive pressure acts.