Blood Circuit Temperature Modeling for Remote Core Sensing

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Solution Overview

Problem

Existing extracorporeal blood treatment systems face challenges in accurately measuring and controlling patient core temperature due to heat transfer variations in the blood circuit, particularly when temperature sensors are located remotely from the patient, leading to inaccuracies in temperature readings.

Innovation Solution

A method that involves measuring blood temperature at different flow rates and using thermal models to calculate the core temperature, incorporating heat transfer coefficients and ambient temperature estimation, allowing for recursive calculations to refine the inlet temperature estimation and correct for heat exchange biases in the blood circuit.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If temperature sensors are located remotely from the patient in the blood circuit, then the system can measure blood temperature, but the temperature readings become inaccurate due to heat transfer variations in the blood circuit

Engineering Contradiction:
Improvetemperature reading accuracyVSAvoidtemperature measurement system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system changes the flow rate parameter of blood through the circuit to create different thermal conditions. By measuring temperature at multiple flow rates and using thermal models to calculate heat transfer coefficients, the system can compensate for heat exchange between blood and environment, thereby improving temperature measurement accuracy despite remote sensor placement

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system uses feedback by measuring temperature at multiple flow rates and using this information to calculate heat transfer coefficients. This feedback loop allows the system to correct for heat exchange effects and determine accurate blood temperature even when sensors are located remotely in the blood circuit

Inventive Principle:
Principle #23Feedback

2Measurement precision

If temperature sensors are placed close to the patient, then temperature readings are more accurate, but the system cannot account for heat transfer dynamics in the blood circuit

Engineering Contradiction:
Improvecore temperature estimation accuracyVSAvoidtemperature control difficulty
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system varies the flow rate parameter and measures temperature responses to calculate heat transfer coefficients. This allows the system to model and compensate for heat exchange dynamics, improving core temperature estimation accuracy while maintaining operational simplicity through automated calculations

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system performs preliminary measurements at multiple flow rates to calculate heat transfer coefficients before determining the final core temperature. This preliminary action of characterizing heat transfer dynamics enables more accurate temperature control during actual treatment operations

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If multiple flow rate measurements are taken to calculate heat transfer coefficients, then temperature measurement accuracy improves, but the measurement time increases

Engineering Contradiction:
Improveinlet temperature calculation accuracyVSAvoidtemperature measurement time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system uses periodic flow rate changes to gather temperature data at multiple flow rates. By systematically varying flow rates and measuring temperature responses, the system can calculate heat transfer coefficients and improve inlet temperature accuracy through structured periodic measurements

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables accurate estimation of patient core temperature, even with remote temperature sensing, by accounting for heat transfer dynamics, thus improving temperature control and detection of abnormal conditions during treatments.

Implementation Method 1

heat transfer between the blood and the external environment of the blood circuit

Methodology Applied
Scientific EffectHeat transfer: Conduction (thermal)

Implementation Method 2

heat gain or loss caused by heat transfer between the blood and the external environment

Methodology Applied
Scientific EffectConvection: Convection

Implementation Method 3

calculating the heat lost up to the point where the temperature is measured

Methodology Applied
Scientific EffectHeat transfer: Conduction (thermal)

Implementation Method 4

the heat transfer properties of the tube are known (that is the internal and external heat transfer coefficient, tube conductivity)

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Data Source

PatentUS11090423B2Body temperature measurement devices, methods, and systems
Publication Date: 2021.08.17 NXSTAGE MEDICAL INC
  • US11090423B2 patent drawing
  • US11090423B2 patent drawing
  • US11090423B2 patent drawing

AI summary

A core temperature measurement may be made by varying the heat transfer dynamics of a blood circuit and fitting parameters of a blood circuit heat transfer configuration to measurements under the varied conditions. Then the input temperature of the patient core can be extracted from the model and a current temperature measurement remote from the patient core and optionally other measurements such as blood flow rate.