Blood Sample Clotting Time Control System

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Solution Overview

Problem

Current methods for processing blood samples in clinical diagnosis often result in incomplete clotting, leading to latent fibrin formation, which can cause analyzer malfunctions and provide incorrect results.

Innovation Solution

A method and system for setting a clotting start time and wait time for blood samples in a test system, allowing for automated transport to a centrifuge upon completion of clotting, ensuring reliable results by minimizing latent fibrin in serum.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If blood samples are processed quickly to improve productivity, then processing speed increases, but clotting may be incomplete leading to latent fibrin formation and incorrect results

Engineering Contradiction:
Improveprocessing speedVSAvoidclotting completeness
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system performs preliminary actions by automatically setting the clotting start time and calculating the required clotting wait time before processing begins. The controller pre-determines the optimal clotting duration based on sample characteristics and automatically initiates the clotting process, ensuring adequate clotting time is allocated before centrifugation and analysis, thus preventing latent fibrin formation while maintaining efficient workflow

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system implements feedback mechanisms by monitoring the clotting process through automated time tracking and sample status detection. The controller receives feedback on clotting progression and automatically adjusts the processing timeline, triggering centrifugation only when clotting is complete, thereby ensuring reliable results while optimizing processing speed through intelligent control

Inventive Principle:
Principle #23Feedback

2Reliability

If manual monitoring of clotting time is used to ensure reliability, then clotting completeness improves, but labor requirements and operational complexity increase

Engineering Contradiction:
Improveclotting completenessVSAvoidoperational simplicity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The system enables self-service by automatically setting clotting start time, calculating required wait time, monitoring clotting progression, and triggering centrifugation without manual intervention. The test system autonomously manages the entire clotting process, eliminating the need for manual time tracking and monitoring while ensuring complete clotting through automated control mechanisms

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system replaces manual mechanical monitoring with automated electronic control. The controller uses electronic timing mechanisms, sensors, and automated decision-making algorithms to monitor and manage clotting time, substituting human operators with an automated control system that ensures reliable clotting completion while simplifying operations through automation

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Ensures adequate clotting time for blood samples, reducing the presence of latent fibrin and providing reliable test results by automatically processing samples once clotting is complete.

Implementation Method 1

automatically providing the blood sample to a centrifuge of the test system

Methodology Applied
Scientific EffectCentrifugal force: Centrifugal Force

Data Source

PatentUS20230324365A1Setting clotting time for blood samples
Publication Date: 2023.10.12 BECKMAN COULTER INC
  • US20230324365A1 patent drawing
  • US20230324365A1 patent drawing
  • US20230324365A1 patent drawing

AI summary

Embodiments of the present disclosure relate to a method, system and apparatus for setting a clotting time for a blood sample contained in a container in a laboratory device or test system, which includes setting a clotting start time for the blood sample, setting a clotting wait time to allow for the blood sample to clot, and on positive determination of the completion of the clotting wait time, automatically providing the blood sample for further processing in the laboratory.