Centrifugal Blood Filter Port Layout for White Blood Cell Removal
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing blood transfusion systems struggle to effectively remove white blood cells from blood components, necessitating a more suitable filtration method.
Innovation Solution
A filter device mounted on a centrifugal separator, featuring a specific arrangement of spaces, ports, and a white-blood-cell removal filter, which utilizes centrifugal force to separate and filter out white blood cells efficiently.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a filter device is mounted on a centrifugal separator to remove white blood cells, then white blood cell removal effectiveness is improved, but device complexity increases due to the additional filter component and specialized space arrangement
Solution Approach 1:
The filter device is nested within the centrifugal separator structure, with the filter housing integrated into the separator's body. The first space and second space are arranged concentrically around the rotation center, allowing the filter system to occupy minimal additional space while maintaining effective white blood cell removal functionality.
Solution Approach 2:
The patent utilizes the radial dimension of the centrifugal separator by arranging the first space and second space in the radial direction from the rotation center. The inlet port and communication port are positioned at different radial distances, creating a multi-dimensional flow path that enhances separation efficiency without increasing axial height.
2Reliability
If the inlet port and communication port are located between the center line and rotation center, then white blood cell removal efficiency is improved through better centrifugal separation, but the available space for port placement is reduced
Solution Approach 1:
The patent applies local quality by positioning ports at specific radial locations where the centrifugal force gradient provides optimal separation. The inlet port is placed at a larger radial distance while the communication port is positioned closer to the rotation center, creating localized flow conditions that maximize white blood cell removal efficiency in the critical separation zone.
3Reliability
If the first space and second space are arranged in the first direction intersecting the centrifugal direction, then blood flow path length is increased for better filtration, but the device volume increases
Solution Approach 1:
The patent resolves the volume issue by arranging the first space and second space in the radial direction (first direction) rather than extending axially. This dimensional change allows the blood to traverse a longer effective filtration path through the centrifugal field without proportionally increasing the overall device volume, as the spaces are stacked radially around the rotation center.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The filter device effectively removes white blood cells by leveraging centrifugal force and filter design, ensuring smooth blood extraction and reliable white blood cell removal without backflow or residual contamination.
Implementation Method 1
a first space which is formed in a housing and into which blood flows through an inlet port; a second space which is formed in the housing and from which the blood flows out through an outlet port; a partition wall that separates the first space and the second space; a communication port that establishes communication between the first space and the second space; and a white-blood-cell removal filter that is disposed in the second space and that removes a white blood cell contained in the blood, wherein the first space and the second space are arranged in a first direction intersecting a centrifugal direction in which a centrifugal force is applied
Implementation Method 2
a white-blood-cell removal filter that is disposed in the second space and that removes a white blood cell contained in the blood
Data Source
Figure 1
Figure 2
Figure 3
AI summary
A filter device (10) according to the present invention is to be mounted on a centrifugal separator (50) and includes: a first space (18) into which blood flows; a second space (20) from which the blood flows out; a partition wall (22) separating the first space and the second space; a communication port (28) establishing communication between the first space and the second space; and a white-blood-cell removal filter (24) disposed in the second space. The first space and the second space are arranged in a first direction (D1) intersecting a centrifugal direction (DC), and the inlet port (14a) and the communication port are located between a center line (C12) along the first direction and a rotation center (LA) of the centrifugal separator.