Extracorporeal Blood Flow Control With Automatic Mode Switching

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Solution Overview

Problem

Centrifugal pumps in heart-lung machines require complex manual operations to switch between flow control and speed control modes and to manage electronic remote clamps, posing risks due to potential user errors.

Innovation Solution

A system with a controller that automatically switches between flow and speed control modes and manages the electronic remote clamp based on trigger conditions, using sensors for blood flow, level, and air bubbles, simplifying operations by eliminating the need for manual button presses.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual operation mode switching and clamp management are used, then the system provides flexible control, but the complexity of operation increases and user errors may occur

Engineering Contradiction:
Improveoperation simplicityVSAvoidcontrol system complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The control system automatically detects trigger conditions (such as air bubbles, blood flow issues) and autonomously switches between flow control mode and speed control mode, and automatically activates the electronic remote clamp when needed. This self-service mechanism eliminates the need for manual monitoring and intervention, reducing operational complexity while maintaining appropriate control flexibility

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system continuously monitors blood flow parameters, air bubble presence, and other critical variables through sensors. Based on this feedback, the controller automatically adjusts operating modes and clamp status. This closed-loop feedback system replaces complex manual decision-making with automated responses, simplifying operation while preserving control precision

Inventive Principle:
Principle #23Feedback

2Reliability

If automatic mode switching and clamp management are implemented, then the risk of user errors is reduced, but the device complexity increases

Engineering Contradiction:
Improveoperational safetyVSAvoidcontrol system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The controller autonomously monitors blood flow conditions, air bubble presence, and other parameters, then automatically switches between flow control and speed control modes and activates the electronic remote clamp when trigger conditions are detected. This eliminates human error in mode switching and clamp management while maintaining appropriate safety responses

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system proactively detects potential problems (air bubbles, flow interruptions) before they become critical and preemptively switches modes or activates the clamp. This preliminary action prevents harmful situations from developing, enhancing reliability without requiring complex manual intervention protocols

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Simplifies the operation of centrifugal pumps by automating mode transitions and clamp management, reducing the risk of user errors and ensuring safer blood flow regulation in extracorporeal circulation.

Implementation Method 1

a centrifugal pump fluidly coupled to the blood reservoir and the oxygenator and configured to pump the blood from the blood reservoir through blood flow lines (e.g., tubing) to the oxygenator and back to the patient

Methodology Applied
Scientific EffectCentrifugal force: Centrifugal Force

Data Source

PatentUS12478718B2Regulating blood flow in extracorporeal circulation
Publication Date: 2025.11.25 LIVANOVA DEUT GMBH
  • US12478718B2 patent drawing
  • US12478718B2 patent drawing
  • US12478718B2 patent drawing

AI summary

A system for regulating blood flow in extracorporeal circulation, and including a blood reservoir to receive blood from a patient, an oxygenator to condition the blood, a centrifugal pump to pump the blood from the blood reservoir to the oxygenator and back to the patient, an electronic remote clamp to regulate flow of the blood, and a controller to operate in a flow control mode and a speed control mode. The controller includes an operational element to set a blood flow value in the flow control mode and to set a speed of the centrifugal pump in the speed control mode. The controller to automatically switch between the flow control mode and the speed control mode in response to one or more trigger conditions and to automatically switch between the speed control mode and the flow control mode in response to opening the electronic remote clamp.