Blood Flow Image Diagnosing Device Pigment Correction
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Solution Overview
Problem
Conventional blood flow image diagnosing devices display varying blood flow measurements due to differences in pigment concentration among individuals, making it difficult to compare values across different races, as the contrast of speckle images is affected by light scattering and absorption in tissues like the retina and skin.
Innovation Solution
A blood flow image diagnosing device with a pigment concentration correction system that calculates and applies correction coefficients based on laser reflectance to standardize blood flow measurements, using a laser reflectance computation section and correction coefficient creation section to adjust blood flow maps according to the pigment concentration of the observation region.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If laser light is applied to measure blood flow in biotissue, then blood flow speed can be imaged, but the measured value varies due to pigment concentration differences in the tissue
Solution Approach 1:
The system measures the actual blood flow value and pigment concentration, then uses feedback control to apply a correction coefficient that compensates for pigment effects. The correction coefficient is determined based on the measured pigment concentration, creating a closed-loop system that adjusts the blood flow measurement to eliminate racial differences in pigment concentration.
Solution Approach 2:
The invention changes the parameter of the blood flow measurement by introducing a correction coefficient that is applied to the raw measurement. This parameter transformation converts the pigment-affected measurement into a standardized value that can be compared across different racial groups with different pigment concentrations.
2Adaptability or versatility
If conventional blood flow measurement is used, then blood flow distribution can be displayed, but values cannot be compared across different races due to pigment differences
Solution Approach 1:
The system adds a universal correction function that can be applied across different racial groups. The correction coefficient mechanism serves multiple functions: it corrects for pigment differences, enables cross-race comparison, and maintains measurement accuracy. This universal approach allows the same measurement system to accurately measure and compare blood flow across diverse populations.
3Measurement precision
If pigment concentration correction is applied, then standardized blood flow values can be obtained, but additional computation is required
Solution Approach 1:
The system performs preliminary measurement of pigment concentration using the same laser light that measures blood flow. By obtaining the pigment concentration data first, the system can then calculate the correction coefficient and apply it to the blood flow measurement. This preliminary action approach integrates the correction process into the existing measurement workflow without requiring separate complex measurement systems.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach allows for standardized comparison of blood flow values across different races by suppressing the influence of pigment concentration, enabling accurate and consistent measurement and display of blood flow data.
Implementation Method 1
a laser light irradiation system for applying laser light to an observation region of a biotissue having blood cells; a light receiving section having a plurality of pixels and adapted to detect reflection light from the observation region of the biotissue
Implementation Method 2
leads a so-called speckle image (an image of random speckle pattern formed as a result of interference of reflection light from the blood cells) to an image sensor such as a solid state imaging device (CCD or CMOS)
Data Source
AI summary
A blood flow image diagnosing device of the present invention includes a laser light irradiation system for applying laser light to an observation region of a biotissue having blood cells; a light receiving section having a plurality of pixels and adapted to detect reflection light from the observation region of the biotissue; an image capturing section for successively capturing a plurality of images on the basis of a signal from the light receiving section; an image storage section for storing the plurality of images; a computation section for computing the speed of blood flow within the biotissue from time course changes of output signals of the pixels throughout the stored images; and a display section for displaying a two-dimensional distribution which is the result of the computation as a blood flow map. The computation section includes a pigment concentration correction section.