Blood Glucose Monitoring with Dynamic Insulin Sensitivity

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Solution Overview

Problem

Existing automated blood glucose monitoring systems rely on a fixed insulin sensitivity coefficient, failing to account for short-term variations, leading to unsuitable insulin doses and risks of hyperglycemia or hypoglycemia due to the inability to adjust in real-time.

Innovation Solution

An automated system that calculates a patient-specific insulin sensitivity coefficient using a mathematical model based on real-time blood glucose data, incorporating a history of insulin injections and glucose ingestion, allowing for real-time adjustments to ensure accurate insulin dosing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a fixed insulin sensitivity coefficient is used in automated blood glucose monitoring systems, then the system is simple to operate and implement, but it cannot account for short-term variations in patient sensitivity, leading to unsuitable insulin doses and risks of hyperglycemia or hypoglycemia

Engineering Contradiction:
Improveaccuracy of insulin dosingVSAvoidcomplexity of coefficient calculation system
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system automatically calculates and updates the insulin sensitivity coefficient using the patient's own historical data (blood glucose measurements, insulin injections, meal history) without requiring external intervention or complex manual calibration, enabling real-time adaptation while maintaining ease of use

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The insulin sensitivity coefficient transitions from a static fixed value to a dynamic parameter that automatically updates in real-time based on changing patient conditions, allowing the system to adapt to short-term variations in sensitivity while managing complexity through automated calculations

Inventive Principle:
Principle #15Dynamics

2Adaptability or versatility

If complex methods are used to determine insulin sensitivity coefficient taking into account blood sugar history, insulin injection history, and meal history, then real-time adjustment is possible, but the implementation becomes complex and requires long past observation periods

Engineering Contradiction:
Improvereal-time adjustment capabilityVSAvoidcomplexity of data processing and calculation
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system pre-processes and stores patient data (blood glucose, insulin injections, meals) in structured formats during routine monitoring, preparing the data in advance for rapid coefficient calculation when needed, enabling real-time adaptation without complex on-demand processing

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system calculates the insulin sensitivity coefficient by analyzing changes in blood glucose levels in response to insulin injections and meal intake, using parameter variations from historical data to determine the optimal coefficient, enabling real-time adjustment through systematic parameter analysis rather than complex algorithms

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP3796838B1Automated system for monitoring a patient's blood sugar
Publication Date: 2022.07.20 COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
  • EP3796838B1 patent drawingFigure 1~3
  • EP3796838B1 patent drawingFigure 4A~5
  • EP3796838B1 patent drawingFigure 6~9

AI summary

The invention relates to an automated system for monitoring a patient's blood sugar, comprising a blood sugar sensor (101) and a processing and control unit (105), in which the processing and control unit (105) is configured to calculate, on the basis of a first mathematical model fCR specific to the patient and taking into account a single blood sugar value Gr measured by the sensor, a coefficient CR representing the insulin sensitivity of the patient.