Blood Pressure Sensor Using Pulse Transit Time Without Calibration

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Solution Overview

Problem

Conventional methods for measuring blood pressure using pulse transit time (PTT) require external calibration with a blood pressure cuff, which is invasive and less accurate for direct systolic blood pressure measurement.

Innovation Solution

A body-worn sensor system that measures PTT and optical waveforms without external calibration, using inflatable armbands and pressure sensors to apply pressure to the arm, allowing for continuous blood pressure measurement through pressure-dependent and pressure-free techniques, directly measuring systolic and diastolic blood pressures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional PTT measurement methods are used, then blood pressure can be measured, but external calibration with a blood pressure cuff is required which is invasive and less accurate

Engineering Contradiction:
Improveblood pressure measurement accuracyVSAvoidmeasurement process complexity
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system performs self-calibration by automatically determining the relationship between PTT and blood pressure using pressure-dependent measurements during inflation, eliminating the need for external calibration equipment and manual calibration procedures

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces the mechanical external blood pressure cuff with an integrated optical and electrical sensing system that measures blood pressure directly through non-contact methods, substituting mechanical compression with optical waveform analysis

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Productivity

If conventional cuff-based methods are used, then blood pressure measurement can be performed, but measurement time and variability increase

Engineering Contradiction:
Improvemeasurement speedVSAvoidmeasurement time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The system enables continuous blood pressure monitoring by continuously measuring PTT and optical waveforms during the inflation process, eliminating the need to wait for cuff deflation and manual reading, thus reducing measurement time and increasing productivity

Inventive Principle:
Principle #20Continuity of useful action

3Ease of operation

If external calibration is used, then measurement can be performed, but patient comfort is reduced due to cuff application and removal

Engineering Contradiction:
Improvepatient comfortVSAvoidmeasurement accuracy
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent replaces the mechanical cuff system with an integrated sensor system that uses optical and electrical measurements to determine blood pressure, eliminating the need for physical cuff application and removal while maintaining measurement reliability through direct waveform analysis

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables continuous, accurate measurement of blood pressure without external calibration, improving accuracy and comfort by directly measuring systolic blood pressure and indirectly determining diastolic pressure, reducing measurement time and variability compared to conventional cuff-based methods.

Implementation Method 1

Pulse oximetry is typically measured with a bandage or clothespin-shaped sensor that attaches to a patient's finger, and includes optical systems operating in both the red and infrared spectral regions. A photodetector measures radiation emitted from the optical systems that transmits through the patient's finger.

Methodology Applied
Scientific EffectOptical transmission: Absorption (EM radiation)

Implementation Method 2

These disposable sensors typically include an armband that features an inflatable air bladder coupled to a pressure sensor

Methodology Applied
Scientific EffectPressure sensing: Piezoresistive Effect

Data Source

PatentEP2162059B1Vital sign monitor and method for measuring blood pressure using optical, electrical, and pressure waveforms
Publication Date: 2021.01.13 SOTERA WIRELESS INC
  • EP2162059B1 patent drawingFigure 1A~1B
  • EP2162059B1 patent drawingFigure 2
  • EP2162059B1 patent drawingFigure 3

AI summary

A method and apparatus for continuous measurement of blood pressure, based on pulse transit time, which does not require any external calibration. This technique, referred to herein as the 'composite technique', is carried out with a body- worn sensor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of disposable sensors, typically placed on the patient's right arm and chest, connect to the body sensor and measure a time-dependent electrical waveform, optical waveform, and pressure waveform. The disposable sensors typically include an armband that features an inflatable bladder coupled to a pressure sensor, at least 3 electrical sensors (e.g. electrodes), and an optical sensor (e.g., a light source and photodiode) attached to a wrist-worn band.