Blood Purification Device Circulating Circuit Design
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Solution Overview
Problem
Current blood purification devices face challenges in efficiently removing pathogenic substances from plasma components at low blood flow rates, leading to extended treatment times and increased patient invasiveness, particularly when using direct needle puncture methods.
Innovation Solution
A blood purification device with a circulating circuit that connects the blood reinfusion-side circuit to the blood removal-side circuit, utilizing a circulating pump to circulate blood and a plasma pump to separate plasma components, allowing for repeated plasma separation and increased treated plasma proportion, thereby enhancing removal efficiency and reducing treatment time.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If direct needle puncture is used for vascular access, then invasiveness and infection risk are reduced, but blood flow rate decreases
Solution Approach 1:
The patent combines the blood removal-side circuit and blood reinfusion-side circuit into a single integrated blood circuit system, allowing low-flow direct needle puncture to be compensated by circuit-level optimization. The circuits are merged to enable efficient plasma separation and return flow management, resolving the contradiction between low invasiveness and sufficient blood flow rate for effective therapy.
Solution Approach 2:
The patent implements dynamic flow management by using a blood pump to actively control blood flow through the circuit, transforming the static low-flow needle puncture into a dynamic system that can maintain adequate flow rates for plasma separation despite the low-invasiveness access method.
2Object-affected harmful factors
If low blood flow rate is used, then patient physical load is reduced, but treatment time extends
Solution Approach 1:
The patent ensures continuous plasma separation and blood circulation through the integrated circuit system with pump-driven flow. The continuous operation of the plasma separator and efficient return flow path maintain therapeutic effectiveness despite low blood flow rates, preventing treatment time extension that would normally result from reduced flow.
Solution Approach 2:
The patent implements flow rate monitoring and pump control mechanisms that provide feedback to maintain optimal circulation. This feedback system ensures that even at low blood flow rates, the plasma separation process remains efficient and treatment objectives are met within reasonable timeframes.
3Productivity
If plasma components are separated and treated, then pathogenic substance removal efficiency increases, but device complexity increases
Solution Approach 1:
The patent designs the blood circuit to serve multiple functions: blood removal, plasma separation, treated plasma return, and waste plasma disposal, all within a single integrated system. This multi-functionality achieves high pathogenic substance removal efficiency without proportionally increasing device complexity, as the same circuit infrastructure supports multiple therapeutic objectives.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device achieves higher removal efficiency of pathogenic substances, allowing for treatment times comparable to those with catheterization methods, while maintaining low invasiveness and reducing the physical load on patients.
Implementation Method 1
a plasma separator configured to separate plasma components from the blood
Implementation Method 2
a blood pump configured to pump the blood in the blood circuit
Implementation Method 3
a circulating pump configured to circulate the blood in the circulating circuit to the blood removal-side circuit
Implementation Method 4
a plasma pump configured to pump the plasma components in the plasma circuit
Data Source
Figure 1
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AI summary
A blood purification device 1A includes: a blood circuit 20 including a blood removal-side circuit 2 that carries blood taken from a subject 100 to a plasma separator 5, and a blood reinfusion-side circuit 12 that returns the blood passing through the plasma separator 5 to the subject 100; a circulating circuit 14 that connects the blood reinfusion-side circuit 12 to the blood removal-side circuit 2; a plasma circuit 6A that carries plasma components separated by the plasma separator 5; and a control unit 16 that controls blood flow so that a portion of the blood flowing in the blood reinfusion-side circuit 12 is circulated to the circulating circuit 14 to be flown to the blood removal-side circuit 2 when the blood in the blood circuit 20 is being pumped and a portion of the plasma components separated by the plasma separator 5 is being pumped to the plasma circuit 6A.