Blood Purification Apparatus Real-Time Clear Space Calculation

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Solution Overview

Problem

Existing blood purification methods require storing all waste dialysate for calculating clear space, leading to increased apparatus size and preventing real-time calculation.

Innovation Solution

A blood purification apparatus with a concentration-detecting unit that establishes equilibrium between waste dialysate and blood concentrations, allowing real-time clear space calculation using a control unit, storage unit, and clear-space-calculating unit, without the need for storing all waste dialysate.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If all waste dialysate is stored to calculate clear space, then clear space can be calculated, but the apparatus size increases

Engineering Contradiction:
Improveclear space calculationVSAvoidapparatus size
Core Design Contradiction:
Measurement precisionVSVolume of stationary object

Solution Approach 1:

The invention extracts only the essential information (dialysate concentration) from the waste dialysate using a concentration detecting unit, rather than storing all the waste dialysate. This allows clear space calculation to be performed using minimal stored data (concentration values) instead of storing large volumes of actual dialysate, thereby reducing apparatus size while maintaining measurement capability

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The invention creates a digital representation (copy) of the waste dialysate properties by detecting and storing concentration values. Instead of storing the physical substance (waste dialysate), the system stores informational copies (concentration data) that are sufficient for clear space calculation, dramatically reducing the space required while preserving the essential measurement function

Inventive Principle:
Principle #26Copying

2Measurement precision

If all waste dialysate is stored to calculate clear space, then clear space can be calculated, but real-time calculation is prevented

Engineering Contradiction:
Improveclear space calculationVSAvoidreal-time calculation capability
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The system performs preliminary detection of dialysate concentration continuously during the blood purification treatment. By detecting and storing concentration values in real-time as the treatment progresses, the system prepares the necessary data in advance, enabling immediate clear space calculation without requiring post-treatment analysis of stored waste dialysate

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The invention replaces the mechanical approach of physically storing and analyzing waste dialysate with an informational approach using optical or electromagnetic detection. The concentration detecting unit measures dialysate properties without requiring physical retention of the fluid, enabling real-time data acquisition and immediate calculation, thus eliminating the delay inherent in physical storage and batch analysis methods

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables real-time calculation of clear space, maintaining apparatus size while accurately representing the volume of purification achieved during blood purification treatment.

Implementation Method 1

a concentration-detecting unit that detects a concentration of a predetermined substance in the waste dialysate flowing through the dialysate drain line

Methodology Applied
Scientific EffectLight absorption: Absorption (EM radiation)

Data Source

PatentUS11419963B2Blood purification apparatus
Publication Date: 2022.08.23 NIKKISO CO LTD
  • US11419963B2 patent drawing
  • US11419963B2 patent drawing
  • US11419963B2 patent drawing

AI summary

A blood purification apparatus with a blood circuit that allows a patient's blood to extracorporeally circulate and a blood purifier connected to the blood circuit and that purifies the blood in extracorporeal circulation are attachable, the blood purification apparatus including a dialysate introduction line through which dialysate is introduced into the blood purifier; a dialysate drain line through which waste dialysate resulting from blood purification performed by the blood purifier is drained from the blood purifier; and a concentration-detecting unit that detects a concentration of a predetermined substance in the waste dialysate flowing through the dialysate drain line. The blood purification apparatus includes a control unit that establishes a state of equilibrium where the concentration of the predetermined substance in the waste dialysate flowing through the dialysate drain line and a concentration of the predetermined substance in the blood flowing through the blood circuit are equal or approximate to each other; a storage unit that stores a value detected by the concentration-detecting unit in the state of equilibrium as an equilibrium value; and a clear-space-calculating unit that calculates clear space in accordance with the value detected by the concentration-detecting unit and the equilibrium value stored in the storage unit, the clear space being an index representing a volume of purification of a patient achieved by blood purification treatment.