Blood Sample Agitating Structure Preventing Adherence

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Solution Overview

Problem

Existing blood sample analyzers face challenges in effectively agitating small-volume blood samples, such as peripheral blood, due to poor fluidity and adherence to tube walls, leading to sample loss and measurement inaccuracies.

Innovation Solution

A blood sample analyzer with a sample conveying device and agitating devices that accommodate both small- and common-volume blood samples, using a controller to manage the agitation process, ensuring the sample container's bottom remains lower than the opening to prevent sample loss, and employing magnetic driving mechanisms for precise agitation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If the inverted agitating method is used for small-volume blood samples, then the blood sample can be agitated, but part of the blood sample remains on the cap and wall causing sample loss

Engineering Contradiction:

Improvemeasurement accuracyVSAvoidblood sample loss

Core Design Contradiction:

Measurement precisionVSLoss of substance

Solution Approach 1:

The patent inverts the traditional agitation approach by keeping the blood collection tube upright instead of inverting it. The agitation is achieved by rotating the tube around a horizontal axis while keeping it upright, which prevents blood from adhering to the cap and wall, thereby eliminating sample loss while maintaining effective agitation for measurement accuracy.

Inventive Principle:

Principle #13The other way round (Inversion)

Solution Approach 2:

The patent introduces dynamic agitation by rotating the blood collection tube around a horizontal axis through a predetermined angle range multiple times. This dynamic rotation creates fluid motion that effectively agitates the blood sample without causing it to adhere to the tube walls or cap, solving the sample loss problem while ensuring measurement precision.

Inventive Principle:

Principle #15Dynamics

2Ease of operation

If the same stirring operation is used for common-volume and small-volume blood samples, then the method is simple, but small-volume samples adhere to the cap and wall and do not flow properly

Engineering Contradiction:

Improveoperation simplicityVSAvoidmeasurement accuracy

Core Design Contradiction:

Ease of operationVSMeasurement precision

Solution Approach 1:

The patent applies local quality by providing different agitation methods for different sample volumes. For small-volume samples, the tube is rotated around a horizontal axis while upright. For common-volume samples, the traditional inversion method is used. This localized differentiation ensures optimal agitation for each sample type, maintaining measurement accuracy while keeping operations simple.

Inventive Principle:

Principle #3Local quality

Solution Approach 2:

The patent uses dynamic rotation of the blood collection tube around a horizontal axis for small-volume samples, creating continuous fluid motion that prevents adherence to walls and cap. This dynamic approach maintains ease of operation while significantly improving measurement accuracy for small-volume samples.

Inventive Principle:

Principle #15Dynamics

3Measurement precision

If the blood collection tube is inverted to agitate the blood sample, then the blood can be stirred, but the blood flows along the tube wall under gravity causing sample loss

Engineering Contradiction:

Improvemeasurement accuracyVSAvoidsample loss

Core Design Contradiction:

Measurement precisionVSLoss of energy

Solution Approach 1:

The patent inverts the traditional inversion method by keeping the tube upright during agitation. The tube is rotated around a horizontal axis while maintaining an upright position, which prevents gravity-driven flow along the tube wall and eliminates sample loss while achieving effective agitation for measurement accuracy.

Inventive Principle:

Principle #13The other way round (Inversion)

Solution Approach 2:

The patent uses mechanical rotation to create vibrational motion within the blood sample. By rotating the tube around a horizontal axis, fluid particles experience vibrational forces that create turbulent mixing and effective agitation without the harmful gravitational flow that occurs during inversion, thus preventing sample loss.

Inventive Principle:

Principle #18Mechanical vibration

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution enables uniform agitation of small-volume blood samples without sample loss, improving measurement accuracy and miniaturizing the analyzer while preventing bar code label damage.

Implementation Method 1

employing magnetic driving mechanisms for precise agitation

Methodology Applied

Scientific EffectMagnetic driving: Magnetic Field

Data Source

PatentUS12174209B2Blood sample analyzer with sample agitating structure and blood sample agitating method

Publication Date: 2024.12.24 SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD

AI summary

Disclosed in the present invention is a blood sample analyzer, including a sample conveying device, a first agitating device, a second agitating device and a controller, etc. When the first agitating device drives a sample container placed in a sample container accommodating hole to agitate a blood sample, a bottom of the sample container is kept lower than an opening of the sample container. In addition, the present invention further discloses a blood sample agitating device, a blood sample analysis method, a blood sample agitating method, and a computer storage medium.