Blood Sample Control for Electrical Measurement Accuracy
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Solution Overview
Problem
Existing electric characteristic measuring apparatuses for blood samples do not verify measurement accuracy before conducting measurements, leading to potentially inaccurate results and rendering the blood sample useless if abnormalities are present in the apparatus or measurement procedure.
Innovation Solution
Incorporating a control sample with a liquid containing blood coagulation factors and micro particles, which allows for the verification of measurement accuracy by temporally measuring electric characteristics, enabling the detection of abnormalities in the apparatus or reagents before measuring a blood sample.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If measurement of blood sample is performed without prior verification, then measurement process is efficient, but measurement accuracy cannot be ensured
Solution Approach 1:
The patent applies preliminary action by performing verification measurement using a control sample before measuring the actual blood sample. This allows the measurement system to be validated in advance, ensuring measurement accuracy is confirmed prior to the main measurement process, thereby resolving the contradiction between ensuring accuracy and maintaining efficiency.
2Reliability
If verification measurement is added before blood sample measurement, then measurement accuracy is ensured, but measurement time increases
Solution Approach 1:
The verification measurement is performed as a preliminary action before the main blood sample measurement. By validating the measurement system in advance with a control sample, the patent ensures measurement reliability is confirmed, and this preliminary step prevents potential re-measurements due to errors, thereby managing the time investment effectively.
Solution Approach 2:
The control sample acts as an intermediary between the measurement system validation and the actual blood sample measurement. It serves as a mediator that verifies the measurement system's functionality without being the final object of interest, thus ensuring reliability while minimizing impact on the main measurement process.
3Reliability
If control sample measurement is performed, then apparatus abnormalities are detected, but additional sample preparation is required
Solution Approach 1:
The control sample serves as an intermediary verification tool that detects apparatus abnormalities without requiring complex additional preparation. It is a simple test sample that validates the measurement system's functionality, acting as a mediator between system validation and patient sample measurement, thus maintaining reliability while minimizing added complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Ensures highly reliable measurement data by confirming measurement accuracy before proceeding with the blood sample analysis, preventing issues related to apparatus or reagent abnormalities and enhancing user convenience through efficient QC processes.
Implementation Method 1
measurement means for measuring a dielectric constant of blood arranged between the paired electrodes
Implementation Method 2
application means for applying an alternating-current (AC) voltage across the pair of electrodes
Data Source
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AI summary
To provide a technique which is useful in verification of measurement accuracy before measurement in the measurement of electric characteristics of a blood sample. There is provided a sample for measurement of electric characteristics at least including a liquid containing a blood coagulation factor, and micro particles. The density of each of the micro particles is different from the density of the liquid containing the blood coagulation factor. In addition, there is provided an electric characteristic measuring apparatus and an electric characteristic measuring method as well each using the sample for measurement of electric characteristics.