Blood Sampling Pipette with Anti-Reflux Membrane and Protective Envelope

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Solution Overview

Problem

Current methods for conducting Ultimate Pre-transfusion Control (UPC) on blood transfusion bags using scissors pose risks of contamination and lack precision due to the size of the blood drops obtained, and existing sampling devices can separate inadvertently during handling and centrifugation.

Innovation Solution

A closed tubing system with a built-in sampling device featuring a pipette connected to a self-sealing membrane valve and a protective envelope, allowing for precise blood withdrawal and secure separation, preventing contamination and breakage during handling and centrifugation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If a pipette is connected to the closed tubing of a transfusion bag for sampling, then contamination risks are reduced, but the closed tubing weakens and may separate inadvertently during handling and centrifugation

Engineering Contradiction:
Improvecontamination riskVSAvoidseparation risk
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The orifice is pre-formed in the closed tubing during manufacturing, and the membrane is pre-installed to provide preliminary sealing. This preliminary preparation ensures that the structural integrity is maintained from the outset, preventing inadvertent separation during subsequent handling and centrifugation operations

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

A flexible membrane acts as an intermediary element between the orifice in the closed tubing and the pipette. This membrane provides a reliable sealing interface that prevents both contamination (by blocking the orifice when pipette is not attached) and separation (by distributing mechanical stresses evenly across the connection interface)

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If scissors are used to cut the closed tubing for blood sampling, then blood can be collected, but contamination risks increase and drop size precision is compromised

Engineering Contradiction:
Improveblood collection capabilityVSAvoidcontamination risk
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The sampling function is extracted from the main closed tubing system by creating a dedicated orifice and attaching a separate pipette. This extraction allows blood sampling to be performed through a controlled interface rather than by cutting the tubing, thereby eliminating contamination risks associated with scissors while maintaining ease of operation

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

A localized orifice is created at a specific position on the closed tubing, equipped with a membrane and pipette assembly. This local modification provides precise control over blood extraction at that specific location, ensuring both ease of operation and elimination of contamination risks without affecting the overall integrity of the closed tubing system

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables safe and precise blood sampling from blood transfusion bags, minimizing contamination risks and ensuring the pipette remains securely attached during centrifugation, thus maintaining the integrity of the transfusion bag contents.

Implementation Method 1

an orifice 5 made in the wall of the closed tubing 1 closed off by a membrane 6 composed of an anti-reflux valve which, when removing the pipette, closes and becomes sealed again

Methodology Applied
Scientific EffectAnti-reflux valve mechanism: Valve

Data Source

PatentEP3007622B1Device for sampling a small quantity of blood contained in closed tubing of a blood transfusion bag.
Publication Date: 2017.02.22 CHABRIER REY CATHERINE
  • EP3007622B1 patent drawing
  • EP3007622B1 patent drawing
  • EP3007622B1 patent drawing

AI summary

The device for sampling a small quantity of blood contained in the closed tube (1) of a blood transfusion bag, in particular for carrying out an ultimate pre-transfusion control (CPU), comprises a pipette (7, 8) linked to said closed tube (1). It differs in that it has an anti-reflux valve membrane incorporated into the wall of the closed tube at the point where the latter is linked to the pipette (7, 8); and in that it further comprises a protective case (9) sealingly moulded onto the closed tube (1) around the pipette (8) and the small conduit of same (7). The protective case opens by pulling the walls of same apart, and stays on the tube in order to allow only the pipette to be gripped. The assembly is arranged in such a way that the pipette is capable of being separated manually from the closed tube (1) by a twisting motion.