Automated Blood Separator Controller for Adsorption Flow

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Solution Overview

Problem

Current blood treatment systems that combine blood separation and adsorption devices require significant manual intervention and oversight to ensure proper processing, which can lead to inefficiencies and potential health risks due to the need for manual monitoring of plasma flow and component replacement.

Innovation Solution

A blood treatment system that integrates a blood separation system with an adsorption device, featuring a controller that automatically regulates the fluid flow based on processing parameters such as maximum flow rate and pressure, reducing the need for manual oversight by ensuring controlled and efficient processing of blood components.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual monitoring and intervention are used to ensure proper plasma flow and component replacement in blood treatment systems, then processing safety can be maintained, but system complexity and operational burden increase significantly

Engineering Contradiction:
Improveprocessing safetyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system performs self-monitoring and self-regulation through automated sensors and control algorithms that track plasma flow rates, pressure differentials, and component replacement timing without requiring manual intervention. The controller automatically adjusts pump speeds and valve positions to maintain safe operating parameters

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system incorporates continuous feedback loops where sensors monitor critical parameters (plasma flow rate, pressure, component levels) and feed this information back to the controller, which automatically adjusts system operation to maintain safety margins and prevent hazardous conditions

Inventive Principle:
Principle #23Feedback

2Reliability

If manual oversight is required for blood treatment processing, then processing control can be maintained, but processing efficiency and productivity decrease

Engineering Contradiction:
Improveprocessing controlVSAvoidprocessing efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The system replaces manual mechanical operations with automated electronic control systems. The controller uses electronic signals to regulate pump motors, control valve actuation, and monitor sensors, eliminating the need for manual operation while maintaining precise control over processing parameters

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system autonomously manages the entire blood treatment process including automated pump control, valve sequencing, parameter monitoring, and alarm generation without requiring human intervention, thereby maximizing processing efficiency while maintaining control

Inventive Principle:
Principle #25Self-service

3Ease of operation

If plasma flow rate and pressure are not strictly controlled during adsorption processing, then system operation becomes simpler, but health risks and processing safety deteriorate

Engineering Contradiction:
Improvesystem operation simplicityVSAvoidhealth risks
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

Pressure sensors and flow meters continuously monitor plasma flow rate and pressure differentials across the adsorption column, feeding this data back to the controller which automatically adjusts pump speed and flow control valves to maintain parameters within safe operating limits, preventing hazardous conditions while simplifying operation

Inventive Principle:
Principle #23Feedback

4Productivity

If automated control systems are implemented to regulate fluid flow in blood treatment, then processing efficiency and safety improve, but device complexity increases

Engineering Contradiction:
Improveprocessing efficiencyVSAvoiddevice complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The controller serves multiple functions simultaneously: it controls pump motors, actuates valves, monitors sensors, processes data from multiple sources, generates alarms, and logs operational parameters. This multi-functionality consolidates what could be multiple separate devices into a single integrated control system, improving efficiency while limiting the increase in complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This integration minimizes manual intervention, enhances processing efficiency, and reduces the risk of errors by automating the flow of blood components into and out of the adsorption device, thereby improving the safety and effectiveness of blood treatment procedures.

Implementation Method 1

The adsorption device will remove undesirable substances from the plasma by immuno-adsorption

Methodology Applied
Scientific EffectImmuno-adsorption: Adsorption

Implementation Method 2

Whole blood is typically separated into its constituents through centrifugation

Methodology Applied
Scientific EffectCentrifugal separation: Centrifugal Separation

Data Source

PatentUS11938259B2Systems and methods for use and control of an automated separator with adsorption columns
Publication Date: 2024.03.26 FENWAL INC
  • US11938259B2 patent drawing
  • US11938259B2 patent drawing
  • US11938259B2 patent drawing

AI summary

Blood treatment systems and methods are provided for combining a blood separation system and an adsorption device. The blood separation system is configured to separate a blood component from blood, while the adsorption device is configured to receive at least a portion of the separated blood component and process it. The blood separation system includes a fluid flow element and a controller. The fluid flow element is configured for flowing the separated blood component into the adsorption device. The controller controls the fluid flow element based at least in part on one or more processing parameters. The processing parameters include a maximum flow rate of the separated blood component flowed into the adsorption device, a maximum pressure of the separated blood component flowed into the adsorption device, and/or the volume of fluid in a location of the system.