Blood Test Kit Cold Insulation for Sample Stability
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Solution Overview
Problem
The challenge is to maintain accurate blood analysis results when transporting small volumes of blood for testing, as external temperature fluctuations during mailing can affect the stability and accuracy of blood components, particularly in self-collected samples.
Innovation Solution
A blood test kit equipped with a diluent solution, a separating means for recovering blood plasma, and a cold insulation means to maintain physiological conditions, which includes a cold insulator and a cold-insulated bag to control temperature and stabilize the blood components during transport.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If blood samples are transported without temperature control, then transportation cost and complexity are reduced, but measurement precision deteriorates due to temperature-induced changes in blood components
Solution Approach 1:
The patent applies preliminary action by pre-freezing blood samples before transport and including freezing instructions in the collection kit. This preliminary freezing action ensures that the blood samples remain stable during transportation without requiring active temperature control systems, thereby maintaining measurement precision while avoiding device complexity.
Solution Approach 2:
The invention employs self-service by providing pre-filled freezing bags and clear instructional materials that enable subjects to properly prepare and transport their own blood samples. The system serves itself by using the subject's own freezer and mailing services, eliminating the need for sophisticated temperature control devices while ensuring sample stability.
2Reliability
If small volume blood collection is used, then subject burden and sample loss are reduced, but reliability deteriorates due to insufficient sample volume for comprehensive testing
Solution Approach 1:
The patent applies segmentation by dividing the blood collection process into multiple components: collection tube, separation membrane, freezing bag, and mailing container. This segmentation allows for efficient use of small blood volumes by preventing contamination and degradation, thereby ensuring reliability despite limited sample quantity.
Solution Approach 2:
The invention uses beforehand cushioning by incorporating separation membranes that prevent blood cell degradation and freezing bags that protect the sample during transport. These protective measures are prepared in advance to cushion against potential damage, ensuring sample reliability even when only small volumes are collected.
3Ease of operation
If self-blood collection is implemented, then ease of operation improves, but stability deteriorates due to lack of professional collection control
Solution Approach 1:
The patent employs an intermediary by using a separation membrane as a mediator between the collected blood and the storage environment. This intermediary component prevents direct contact between blood cells and potentially degrading surfaces, maintaining sample stability while allowing easy self-collection by subjects.
Solution Approach 2:
The invention uses disposable single-use components including collection tubes, separation membranes, and freezing bags. These inexpensive disposable items ensure sample stability by eliminating cross-contamination risks while maintaining ease of operation for self-collection, as each component is designed for one-time use only.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution enables high-accuracy blood analysis by controlling temperature variations, allowing for reliable self-blood collection and transportation of small blood volumes, even in high-temperature conditions, and supports various tests, including biochemical and tumor marker analyses.
Implementation Method 1
a cold insulation means for cold-insulating the container
Data Source
AI summary
An object of the present invention is to provide a blood test kit of which a component in a small volume of blood can be mailed in a safe state by controlling the influence of the outside temperature during the mailing, and a highly accurate blood analysis method in which coefficient of variation of a measurement value is reduced. According to the present invention, a blood test kit including a diluent solution for diluting a blood sample; a separating means for recovering blood plasma components from the diluted blood sample; a container for storing the blood plasma components recovered from the diluted blood sample; and a cold insulation means for cold-insulating the container, is provided.